Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL27658979 | 0.85 | CA2 (0.42) | CA2CA4CA1KMT2AMEN1 | |
| Benzoic Acid SCHEMBL2230871 | 0.84 | KMT2A (0.58) | CA2CA1KMT2AMEN1RXFP1 | |
| Acetic Acid SCHEMBL27465373 | 0.81 | MTNR1A (0.53) | KMT2AMEN1RXFP1POLBMTNR1A | |
| Hydrochloric Acid SCHEMBL28169465 | 0.81 | LMNA (0.48) | CA4KMT2AMEN1POLBMTNR1A | |
| Water SCHEMBL16974333 | 0.81 | LMNA (0.48) | CA4KMT2AMEN1POLBMTNR1A | |
| SCHEMBL15709 | 0.81 | LMNA (0.52) | CA4KMT2AMEN1POLBMTNR1A | |
| SCHEMBL167127 | 0.81 | LMNA (0.52) | CA4KMT2AMEN1POLBMTNR1A | |
| Benzene SCHEMBL28097669 | 0.81 | LMNA (0.52) | CA4KMT2AMEN1POLBMTNR1A | |
| Benzoic Acid SCHEMBL28286208 | 0.80 | CA2 (0.71) | CA2CA4CA1ALDH1A1LMNA | |
| Propionic Acid SCHEMBL28882997 | 0.79 | MTNR1A (0.45) | KMT2AMEN1POLBMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3881819-B1 | TWO-DOSAGE-FORM ESSENCE AND PREPARATION METHOD THEREFOR | GUANGZHOU BIOHOPE CO LTD (CN) | 2024-12-25 | — | — | EP | disclosed |
| US-20220062308-A1 | METHODS AND COMPOSITIONS FOR TREATING ROSACEA | HOVIONE SCIENTIA LIMITED (IE) | 2022-03-03 | — | — | US | disclosed |
| US-10668113-B2 | Formulation for targeting cancer in humans and canines using venom | RAMANA VIVEKANANDA (US) | 2020-06-02 | — | — | US | disclosed |
| US-10668130-B2 | Formulation for targeting cancer in humans and canines using chlorotoxin | RAMANA VIVEKANANDA (US) | 2020-06-02 | — | — | US | disclosed |
| US-20180280473-A1 | FORMULATION FOR TARGETING CANCER IN HUMANS AND CANINES USING CHLOROTOXIN | RAMANA VIVEKANANDA (US) | 2018-10-04 | — | — | US | disclosed |
| US-20180280449-A1 | FORMULATION FOR TARGETING CANCER IN HUMANS AND CANINES USING VENOM | RAMANA VIVEKANANDA (US) | 2018-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220062308-A1 | METHODS AND COMPOSITIONS FOR TREATING ROSACEA | CUTA, LIPA, RDX | CA2 1861/4885CA4 2062/4885CA1 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.