SCHEMBL2051552

SCHEMBL2051552

CCCCCCCCCCCCCCOC(CCCCCCC)C(C)CC(O)CO

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.47
PTPN1 P18031 1/20 0.42
LMNA P02545 3/20 0.39
PLA2G2C Q5R387 1/20 0.38
CYP2D6 P10635 2/20 0.38
KDM4E B2RXH2 2/20 0.38
SPHK1 Q9NYA1 1/20 0.38
GMNN O75496 1/20 0.38
POLB P06746 1/20 0.38
THPO P40225 1/20 0.38
MTOR P42345 1/20 0.38
BLM P54132 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
CETP P11597 1/20 0.38
HTT P42858 1/20 0.38
UBE2N P61088 1/20 0.38
MGAM O43451 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL369873 0.85 PTPN1 (0.45) USP2PTPN1LMNACYP2D6KDM4E
SCHEMBL17237498 0.83 PTPN1 (0.43) USP2PTPN1LMNACYP2D6KDM4E
SCHEMBL8636200 0.78 CYP2D6 (0.47) USP2PTPN1LMNACYP2D6KDM4E
SCHEMBL142856 0.78 CYP2D6 (0.47) USP2PTPN1LMNACYP2D6KDM4E
SCHEMBL1890335 0.78 CYP2D6 (0.47) USP2PTPN1LMNACYP2D6KDM4E
SCHEMBL17237496 0.78 USP2 (0.55) USP2LMNAPLA2G2CKDM4EHTT
SCHEMBL5963213 0.78 CYP2D6 (0.47) USP2PTPN1LMNACYP2D6KDM4E
SCHEMBL139954 0.78 CYP2D6 (0.47) USP2PTPN1LMNACYP2D6KDM4E
SCHEMBL9623258 0.78 CYP2D6 (0.47) USP2PTPN1LMNACYP2D6KDM4E
SCHEMBL2385585 0.78 CYP2D6 (0.47) USP2PTPN1LMNACYP2D6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2651370-B1 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, A SILICONE OIL AND A WAX OREAL (FR) 2018-11-14 EP claimed
EP-2723309-B1 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND TWO PARTICULAR DISTINCT SILICONE OILS OREAL (FR) 2018-10-17 EP claimed
EP-2512428-B1 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND A PARTICULAR OIL L'ORÉAL (FR) 2017-04-05 EP claimed
EP-2723309-A2 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND TWO PARTICULAR DISTINCT SILICONE OILS L'Oréal (FR) 2014-04-30 EP claimed
EP-2512427-B1 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND A PARTICULAR ADDITIONAL INGREDIENT OREAL (FR) 2013-11-06 EP claimed
EP-2651370-A2 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, A SILICONE OIL AND A WAX L'Oréal (FR) 2013-10-23 EP claimed
WO-2012175402-A2 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND TWO PARTICULAR DISTINCT SILICONE OILS L'OREAL (FR) 2012-12-27 WO claimed
EP-2512428-A1 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND A PARTICULAR OIL L'Oréal (FR) 2012-10-24 EP claimed
EP-2512427-A1 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND A PARTICULAR ADDITIONAL INGREDIENT L'Oréal (FR) 2012-10-24 EP claimed
WO-2012080165-A2 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, A SILICONE OIL AND A WAX L'OREAL (FR) 2012-06-21 WO claimed
WO-2011073294-A1 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND A PARTICULAR ADDITIONAL INGREDIENT L'OREAL (FR) 2011-06-23 WO claimed
WO-2011073295-A1 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND A PARTICULAR OIL L'OREAL (FR) 2011-06-23 WO claimed
CN-113710329-B Personal care compositions 高露洁-棕榄公司 2024-04-05 CN disclosed
US-10653600-B2 Cosmetic composition comprising a supramolecular compound capable of establishing hydrogen bonds, and two particular distinct silicone oils L'OREAL (FR) 2020-05-19 US disclosed
EP-2651370-B1 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, A SILICONE OIL AND A WAX OREAL (FR) 2018-11-14 EP disclosed
EP-2723309-B1 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND TWO PARTICULAR DISTINCT SILICONE OILS OREAL (FR) 2018-10-17 EP disclosed
WO-2012080165-A2 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, A SILICONE OIL AND A WAX L'OREAL (FR) 2012-06-21 WO disclosed
WO-2011073294-A1 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND A PARTICULAR ADDITIONAL INGREDIENT L'OREAL (FR) 2011-06-23 WO disclosed
WO-2011073295-A1 COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND A PARTICULAR OIL L'OREAL (FR) 2011-06-23 WO disclosed
US-20100028277-A1 COMPOSITION CONTAINING A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10653600-B2 Cosmetic composition comprising a supramolecular compound capable of establishing hydrogen bonds, and two particular distinct silicone oils CHEK1, STIM1, FASN USP2 3353/4885PTPN1 1543/4885LMNA 2551/4885
US-20100028277-A1 COMPOSITION CONTAINING A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND COSMETIC TREATMENT PROCESS CUTA, ALOX15, DSG1 USP2 2479/4885PTPN1 3269/4885LMNA 2083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.