Sugi Predict

Sugi Predict / Compounds / SCHEMBL142856

SCHEMBL142856

SCHEMBL142856

CCCCCCCCCCCCOC(CCCCCCCCCCCC)C(O)CO

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 2/20 0.47
▸ LMNA P02545 2/20 0.47
▸ SPHK1 Q9NYA1 2/20 0.47
▸ MAPT P10636 2/20 0.47
▸ HTT P42858 2/20 0.47
▸ GMNN O75496 1/20 0.47
▸ POLB P06746 1/20 0.47
▸ THPO P40225 1/20 0.47
▸ MTOR P42345 1/20 0.47
▸ BLM P54132 1/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ TP53 P04637 1/20 0.47
▸ CYP1A2 P05177 1/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ CETP P11597 1/20 0.47
▸ UBE2N P61088 1/20 0.47
▸ USP2 O75604 1/20 0.46
▸ PTPN1 P18031 1/20 0.44
▸ MGAM O43451 3/20 0.44
▸ ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18139666 1.00 CYP2D6 (0.47) CYP2D6LMNASPHK1MAPTHTT
SCHEMBL9623258 1.00 CYP2D6 (0.47) CYP2D6LMNASPHK1MAPTHTT
SCHEMBL29064944 1.00 CYP2D6 (0.47) CYP2D6LMNASPHK1MAPTHTT
SCHEMBL28434701 1.00 CYP2D6 (0.47) CYP2D6LMNASPHK1MAPTHTT
SCHEMBL5963213 1.00 CYP2D6 (0.47) CYP2D6LMNASPHK1MAPTHTT
SCHEMBL139954 1.00 CYP2D6 (0.47) CYP2D6LMNASPHK1MAPTHTT
SCHEMBL8636200 1.00 CYP2D6 (0.47) CYP2D6LMNASPHK1MAPTHTT
SCHEMBL1890335 1.00 CYP2D6 (0.47) CYP2D6LMNASPHK1MAPTHTT
SCHEMBL2385585 1.00 CYP2D6 (0.47) CYP2D6LMNASPHK1MAPTHTT
SCHEMBL28230194 1.00 CYP2D6 (0.47) CYP2D6LMNASPHK1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079802-A Cationic lipids and compositions thereof — 2026-05-26 — — CN claimed
US-20250352666-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF GENERATION BIO CO (US) 2025-11-20 — — US claimed
EP-4626409-A1 SYNTHETIC SINGLE STRANDED NUCLEIC ACID COMPOSITIONS AND METHODS THEREOF Generation Bio Co. (US) 2025-10-08 — — EP claimed
US-20250249123-A1 LIPIDS AND COMPOSITIONS THEREOF GENERATION BIO CO. 2025-08-07 — — US claimed
WO-2025127402-A1 LIPID FOR ENHANCING IMMUNOGENICITY OF MRNA/LNP VACCINE 한국생명공학연구원 2025-06-19 — — WO claimed
EP-4536197-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF Generation Bio Co. (US) 2025-04-16 — — EP claimed
US-12263228-B2 Lipids and compositions thereof GENERATION BIO CO. (US) 2025-04-01 — — US claimed
WO-2024249298-A2 MODIFIED CLOSED-ENDED DNA (CEDNA) VECTORS, COMPOSITIONS, AND USES THEREOF GENERATION BIO CO. (US) 2024-12-05 — — WO claimed
US-20240382432-A1 SINGLE CHAIN VARIABLE FRAGMENT (SCFV) MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF GENERATION BIO CO. 2024-11-21 — — US claimed
US-20240299580-A1 APOE AND APOB MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF GENERATION BIO CO. 2024-09-12 — — US claimed
CN-117545469-A Cationic lipids and compositions thereof 世代生物公司 2024-02-09 — — CN claimed
WO-2023239756-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF GENERATION BIO CO. (US) 2023-12-14 — — WO claimed
CN-115745788-A Ionizable lipid compound and preparation method and application thereof 国家纳米科学中心 2023-03-07 — — CN claimed
WO-2023287861-A2 SINGLE CHAIN VARIABLE FRAGMENT (SCFV) MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF GENERATION BIO CO. (US) 2023-01-19 — — WO claimed
CN-115504945-A Ionizable heterocyclic lipid molecule and application thereof in preparation of lipid nanoparticles 南京吉迈生物技术有限公司 2022-12-23 — — CN claimed
WO-2022266032-A1 CATIONIC LIPIDS AND COMPOSITIONS THEREOF GENERATION BIO CO. (US) 2022-12-22 — — WO claimed
WO-2022261101-A1 APOE AND APOB MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF GENERATION BIO CO. (US) 2022-12-15 — — WO claimed
WO-2022226008-A2 CATIONIC LIPIDS AND COMPOSITIONS THEREOF GENERATION BIO CO. (US) 2022-10-27 — — WO claimed
CN-114344278-A Nucleic acid delivery vectors and uses thereof 南京吉迈生物技术有限公司 2022-04-15 — — CN claimed
WO-2002087541-A1 LIPID-BASED FORMULATIONS FOR GENE TRANSFER PROTIVA BIOTHERAPEUTICS INC. (CA) 2002-11-07 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240299580-A1 APOE AND APOB MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF LDLR, APOB, APOL1 CYP2D6 3964/4885LMNA 63/4885SPHK1 3627/4885
US-12263228-B2 Lipids and compositions thereof C1R, LIPG, LRBA CYP2D6 2994/4885LMNA 49/4885SPHK1 1286/4885
US-20250352666-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF LIPA, EYA3, EYA2 CYP2D6 4779/4885LMNA 305/4885SPHK1 873/4885
US-20250249123-A1 LIPIDS AND COMPOSITIONS THEREOF C1R, LIPG, LRBA CYP2D6 2994/4885LMNA 49/4885SPHK1 1286/4885
US-20240382432-A1 SINGLE CHAIN VARIABLE FRAGMENT (SCFV) MODIFIED LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF LNPEP, CD47, CD4 CYP2D6 4755/4885LMNA 800/4885SPHK1 2042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.