SCHEMBL2051640

SCHEMBL2051640

Brc1ccc2ccc(Br)cc2c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.72
KDM4E B2RXH2 1/20 0.57
MEN1 O00255 1/20 0.57
ALDH1A1 P00352 1/20 0.57
MAPT P10636 1/20 0.57
KMT2A Q03164 1/20 0.57
BACE1 P56817 2/20 0.48
AHR P35869 3/20 0.46
NR4A2 P43354 1/20 0.46
NOS1 P29475 2/20 0.42
METAP2 P50579 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 1/20 0.42
HTT P42858 1/20 0.42
CSNK2A1 P68400 1/20 0.42
DYRK1A Q13627 1/20 0.42
ALOX15 P16050 1/20 0.41
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
ERN1 O75460 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29371678 1.00 CYP2A6 (0.72) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL148642 0.90 CYP2A6 (0.68) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL29427549 0.90 CYP2A6 (0.68) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL13153611 0.90 CYP2A6 (0.68) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL17849092 0.90 CYP2A6 (0.68) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL23312077 0.90 CYP2A6 (0.68) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL17849089 0.90 CYP2A6 (0.68) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL29353067 0.89 CYP2A6 (0.77) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL192166 0.89 CYP2A6 (0.77) CYP2A6KDM4EMEN1ALDH1A1MAPT
SCHEMBL9566139 0.84 CYP2A6 (0.62) CYP2A6KDM4EMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 461 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110627602-A Organic photoelectric semiconductor material and synthesis method and application thereof 天津大学 2019-12-31 CN claimed
CN-104311497-B 1 [7 (1H 1,2,4 triazole 1 base) naphthalene 2 base] 1H 1,2,4 3-triazole compounds and preparation method thereof 天津师范大学 2016-11-30 CN claimed
US-4435222-A HALOGENATED NAPHTHALENES AND BIPHENYLS FOLLOWED BY ALUMUNUM HALIDES PHILLIPS PETROLEUM COMPANY (US) 1984-03-06 US claimed
EP-4688779-A2 NOVEL COMPOUNDS AND USES THEREOF Acelink Therapeutics, Inc. (US) 2026-02-11 EP disclosed
US-20260007075-A1 LIGHT-EMITTING ELEMENT, POLYCYCLIC COMPOUND FOR THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2026-01-01 US disclosed
US-12448353-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2025-10-21 US disclosed
US-12435044-B2 Pyridazinone herbicides and pyridazinone intermediates used to prepare a herbicide FMC CORPORATION (US) 2025-10-07 US disclosed
US-12433152-B2 Compound for organic optoelectronic device, composition for organic optoelectronic device, organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2025-09-30 US disclosed
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 US disclosed
US-20250215030-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 US disclosed
US-20250179103-A1 6-OXODECAHYDROPYRROLO[1,2-A][1,5]DIAZOCINE AND 6-OXODECAHYDRO-4H-PYRROLO[2,1-D][1,5]THIAZOCINE DERIVATIVES AS STAT3 AND STAT6 MODULATORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS RECLUDIX PHARMA, INC. 2025-06-05 US disclosed
US-5068312-A Molding materials formed by reacting dihalogen compounds with a sulfur donor in a solvent BAYER AKTIENGESELLSCHAFT (DE) 1991-11-26 US disclosed
US-5066776-A From dihaloaromatic compound, in situ generation of alkali sulfides BAYER AKTIENGESELLSCHAFT (DE) 1991-11-19 US disclosed
EP-0414079-A2 Process of preparation of polyarylene sulfides BAYER AG (DE) 1991-02-27 EP disclosed
EP-0395883-A2 Mixtures of poly(arylene sulfides) with sulfonic end groups or their derivates with poly(arylene sulfides, and their use BAYER AG (DE) 1990-11-07 EP disclosed
US-4845280-A CATALYTIC CARBONYLATION OF AROMATIC BROMIDES EASTMAN KODAK COMPANY (US) 1989-07-04 US disclosed
US-4767873-A Helical metallocene oligomers and a method for their preparation THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1988-08-30 US disclosed
EP-0236488-A1 HELICAL METALLOCENE OLIGOMERS AND A METHOD FOR THEIR PREPARATION THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1987-09-16 EP disclosed
WO-1987001704-A1 HELICAL METALLOCENE OLIGOMERS AND A METHOD FOR THEIR PREPARATION THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF (US) 1987-03-26 WO disclosed
US-4435222-A HALOGENATED NAPHTHALENES AND BIPHENYLS FOLLOWED BY ALUMUNUM HALIDES PHILLIPS PETROLEUM COMPANY (US) 1984-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12448353-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device OR10J3, PIEZO1, L1CAM CYP2A6 4492/4885KDM4E 2740/4885MEN1 52/4885
US-20250179103-A1 6-OXODECAHYDROPYRROLO[1,2-A][1,5]DIAZOCINE AND 6-OXODECAHYDRO-4H-PYRROLO[2,1-D][1,5]THIAZOCINE DERIVATIVES AS STAT3 AND STAT6 MODULATORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS STAT6, STAT3, STAT1 CYP2A6 941/4885KDM4E 857/4885MEN1 1979/4885
US-20250215030-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A CYP2A6 2129/4885KDM4E 1457/4885MEN1 2739/4885
US-20260007075-A1 LIGHT-EMITTING ELEMENT, POLYCYCLIC COMPOUND FOR THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE SAME NFE2L2, CRY2, CRY1 CYP2A6 1220/4885KDM4E 1339/4885MEN1 1254/4885
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A CYP2A6 2237/4885KDM4E 1488/4885MEN1 2963/4885
US-12433152-B2 Compound for organic optoelectronic device, composition for organic optoelectronic device, organic optoelectronic device and display device OCIAD2, OCIAD1, OXER1 CYP2A6 1291/4885KDM4E 4378/4885MEN1 2840/4885
US-12435044-B2 Pyridazinone herbicides and pyridazinone intermediates used to prepare a herbicide CBR3, CBR1, CYP4F3 CYP2A6 51/4885KDM4E 3021/4885MEN1 3526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.