Sugi Predict

Sugi Predict / Compounds / SCHEMBL2051695

SCHEMBL2051695

SCHEMBL2051695

CC(=O)c1cccc(C)c1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.69
▸ KDM4E B2RXH2 4/20 0.69
▸ HPGD P15428 2/20 0.69
▸ HSD17B10 Q99714 2/20 0.69
▸ CYP3A4 P08684 1/20 0.58
▸ CYP2C9 P11712 1/20 0.58
▸ KMT2A Q03164 1/20 0.58
▸ BRPF1 P55201 1/20 0.52
▸ TRPA1 O75762 1/20 0.50
▸ PLAU P00749 2/20 0.49
▸ F2 P00734 1/20 0.49
▸ F10 P00742 1/20 0.49
▸ PLG P00747 1/20 0.49
▸ PLAT P00750 1/20 0.49
▸ KLK1 P06870 1/20 0.49
▸ KLK5 Q9Y337 1/20 0.49
▸ P2RX1 P51575 1/20 0.49
▸ NPC1 O15118 2/20 0.49
▸ RAB9A P51151 2/20 0.49
▸ HTT P42858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29743740 1.00 ALDH1A1 (0.69) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
SCHEMBL7301332 0.85 THRB (0.50) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
SCHEMBL1758307 0.84 KMT2A (0.78) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL28037743 0.82 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL29499765 0.82 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
SCHEMBL20853594 0.82 ALDH1A1 (0.69) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL25756 0.82 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL8352264 0.82 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL25338040 0.80 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL238307 0.80 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114751870-B 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxybenzoate and derivative thereof, and synthetic method and application thereof 贵州医科大学 2023-10-20 — — CN claimed
CN-114751870-A 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxy benzoate and derivative thereof, and synthesis method and application thereof 贵州医科大学 2022-07-15 — — CN claimed
CN-102796045-B Pyrazoline derivatives, and preparation method and application thereof UNIV SHANDONG 2014-05-28 — — CN claimed
US-20140135359-A1 METHODS OF DESIGNING, PREPARING, AND USING NOVEL PROTONOPHORES MARTINEAU LOUIS C (CA) 2014-05-15 — — US claimed
US-11827657-B2 Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof Boehringer Ingelheim Animal Health USA Inc. (US) 2023-11-28 — — US disclosed
US-11827657-B2 Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof Boehringer Ingelheim Animal Health USA Inc. (US) 2023-11-28 — — US disclosed
CN-114751870-B 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxybenzoate and derivative thereof, and synthetic method and application thereof 贵州医科大学 2023-10-20 — — CN disclosed
CN-116715671-A Application of alpha-chromene spiropiperidine compound in preparation of 5-hydroxytryptamine 2C receptor agonist 苏州大学 2023-09-08 — — CN disclosed
WO-2023072273-A1 POLYCYCLIC COMPOUND AS CBL-B INHIBITOR 先声再明医药有限公司 2023-05-04 — — WO disclosed
CN-115068475-A Application of alpha-chromene spiropiperidine compounds in preparation of 5-hydroxytryptamine 2C receptor agonists 苏州大学 2022-09-20 — — CN disclosed
CN-109415304-B Method for producing iron complex and method for producing ester compound using iron complex 株式会社可乐丽 2022-07-22 — — CN disclosed
CN-114751870-A 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxy benzoate and derivative thereof, and synthesis method and application thereof 贵州医科大学 2022-07-15 — — CN disclosed
CN-88101674-A Chromone derivative — 1988-10-05 — — CN disclosed
US-4775747-A PIGMENTS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1988-10-04 — — US disclosed
EP-0283761-A1 Chromone derivatives Takeda Chemical Industries, Ltd. (JP) 1988-09-28 — — EP disclosed
US-4670486-A Polymer composition pigmented with copper or nickel complexes of ligands containing a semicarbazone moiety CIBA-GEIGY CORPORATION (US) 1987-06-02 — — US disclosed
US-4639477-A AZO DYES CIBA-GEIGY CORPORATION (US) 1987-01-27 — — US disclosed
EP-0169167-A2 Process for dyeing high-molecular organic materials, and metal complexes CIBA-GEIGY AG (CH) 1986-01-22 — — EP disclosed
EP-0168343-A2 Metal complexes, process for their preparation and their use in dyeing high-molecular organic materials CIBA-GEIGY AG (CH) 1986-01-15 — — EP disclosed
US-4002423-A Benzofuran derivatives process for their preparation and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11827657-B2 Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof JAK3, JAK1, JAK2 ALDH1A1 3977/4885KDM4E 1548/4885HPGD 3338/4885
US-20140135359-A1 METHODS OF DESIGNING, PREPARING, AND USING NOVEL PROTONOPHORES UQCRC2, UQCRC1, TIMM50 ALDH1A1 3040/4885KDM4E 4121/4885HPGD 177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.