Hydroxytoluic Acid

Hydroxytoluic Acid

SCHEMBL29499765

Cc1cccc(C(=O)O)c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 1.00
KDM4E B2RXH2 4/20 1.00
HPGD P15428 3/20 1.00
HSD17B10 Q99714 2/20 1.00
CYP3A4 P08684 2/20 0.75
CYP2C9 P11712 2/20 0.75
KMT2A Q03164 2/20 0.75
ALB P02768 1/20 0.57
MMP2 P08253 1/20 0.57
MYC P01106 1/20 0.57
TRPA1 O75762 2/20 0.55
NAPRT Q6XQN6 2/20 0.55
MEN1 O00255 1/20 0.55
AKR1B10 O60218 1/20 0.55
ABCB11 O95342 1/20 0.55
DHFR P00374 1/20 0.55
LMNA P02545 1/20 0.55
MPO P05164 1/20 0.55
CYP1A2 P05177 1/20 0.55
CHRM1 P11229 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroxytoluic Acid SCHEMBL8352264 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL28037743 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL25756 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL11527547 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL31174935 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL25338040 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL30538825 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL25337502 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL238307 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4
Hydroxytoluic Acid SCHEMBL622892 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHPGDHSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590963-B2 Anti-cancer treatment of preselected subjects and screening methods to identify susceptible subjects TUDAG TU DRESDEN AKTIENGESELLSCHAFT (DE) 2026-03-31 US disclosed
EP-4583870-A2 MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER Mito Biopharma, LLC (US) 2025-07-16 EP disclosed
US-20250213569-A1 METHODS AND COMPOSITIONS FOR MEASURING AND INHIBITING EXONUCLEASE ACTIVITY NEW YORK UNIVERSITY (US) 2025-07-03 US disclosed
EP-4558117-A2 EXTRACT SOLUTION COMPRISING NYMPHAEA COERULEA FLOWER EXTRACT AND NELUMBO NUCIFERA FLOWER EXTRACT, COMPOSITIONS AND METHODS THEREOF Coty Inc. (US) 2025-05-28 EP disclosed
WO-2025047885-A1 RESIN COMPOSITION 三菱ケミカル株式会社 2025-03-06 WO disclosed
WO-2024054766-A2 MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER MITO BIOPHARMA, LLC (US) 2024-03-14 WO disclosed
WO-2024020463-A2 COSMETIC COMPOSITION COTY INC. (US) 2024-01-25 WO disclosed
EP-4157914-A1 PROCESSES FOR PRODUCING AROMATIC DIAMINE-INITIATED POLYETHER POLYOLS Covestro Deutschland AG (DE) 2023-04-05 EP disclosed
US-20220244263-A1 METHODS FOR TREATING SMALL CELL NEUROENDOCRINE AND RELATED CANCERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-04 US disclosed
WO-2022119854-A1 COMPOUNDS FOR THE TREATMENT OF SARS PURDUE RESEARCH FOUNDATION (US) 2022-06-09 WO disclosed
EP-3962479-A1 KCNT1 INHIBITORS AND METHODS OF USE Praxis Precision Medicines, Inc. (US) 2022-03-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213569-A1 METHODS AND COMPOSITIONS FOR MEASURING AND INHIBITING EXONUCLEASE ACTIVITY DCLRE1B, RNASE1, ADAR ALDH1A1 3389/4885KDM4E 4082/4885HPGD 3531/4885
US-12590963-B2 Anti-cancer treatment of preselected subjects and screening methods to identify susceptible subjects TPM4, TPM3, TAGLN2 ALDH1A1 2279/4885KDM4E 2931/4885HPGD 2813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.