SCHEMBL2051968

SCHEMBL2051968

C=CCC(CC=C)(C(=O)NC(C)(C)C)C(=O)NC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.33
CCR2 P41597 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
EPHX1 P07099 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP3 P08254 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22457414 0.78 CCR2 (0.33) SMN1; SMN2CCR2
SCHEMBL2049096 0.77 MMP1 (0.34) CCR2MMP1MMP2MMP3
SCHEMBL2044114 0.75 CCR2 (0.31) CCR2
SCHEMBL2052082 0.74 FAAH (0.32) SMN1; SMN2KMT2AMMP1MMP2MMP3
SCHEMBL2047446 0.72 TSHR (0.45) CCR2MEN1KMT2AMMP1MMP2
SCHEMBL2051319 0.71 MMP1 (0.36) SMN1; SMN2MEN1KMT2AEPHX1MMP1
SCHEMBL2050892 0.69 CYP2D6 (0.43) MEN1KMT2AEPHX1MMP1MMP2
SCHEMBL6831466 0.69 ALDH1A1 (0.38)
SCHEMBL770755 0.68 CYP2C19 (0.39) MMP1
SCHEMBL2048411 0.67 HTT (0.37) CCR2MMP1MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964691-B2 5,5-diallyl-2,2-dimethyl-1,3-dioxane as monomer units; polymerization catalysts; heat resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-21 US disclosed
US-20080214755-A1 OLEFIN-DIENE COPOLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed
US-20080214754-A1 DIENE POLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed