Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 3/20 | 0.35 |
| ▸ | CYCS | P99999 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20843737 | 0.87 | STAT3 (0.43) | STAT3STAT1TOP1CYCSABCG2 | |
| SCHEMBL20520075 | 0.85 | STAT3 (0.59) | STAT3STAT1TOP1 | |
| SCHEMBL6092415 | 0.83 | STAT3 (0.43) | STAT3STAT1TOP1CYCSPARP1 | |
| SCHEMBL6094135 | 0.81 | STAT3 (0.45) | STAT3STAT1TOP1PARP1 | |
| SCHEMBL28539046 | 0.81 | STAT3 (0.50) | STAT3STAT1TOP1CYCS | |
| SCHEMBL20520148 | 0.79 | STAT3 (0.38) | STAT3STAT1CYCSPARP1 | |
| SCHEMBL20843716 | 0.78 | STAT3 (0.39) | STAT3STAT1ABCG2 | |
| SCHEMBL28539011 | 0.76 | STAT3 (0.43) | STAT3STAT1TOP1 | |
| SCHEMBL8977875 | 0.76 | STAT3 (0.69) | STAT3STAT1TOP1CYCSABCG2 | |
| SCHEMBL30426808 | 0.75 | STAT3 (0.56) | STAT3STAT1TOP1CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107624114-B | Low molecular weight derivatives of carboxamide halogenated porphyrins, namely chlorins and bacteriochlorins, and uses thereof | 卢西蒂恩股份有限公司 | 2021-03-23 | — | — | CN | disclosed |
| US-10450322-B2 | Low molecular weight derivatives of carboxamide halogenated porphyrins, namely chlorins and bacteriochlorins, and their applications thereof | LUZITIN, S.A. (PT) | 2019-10-22 | — | — | US | disclosed |
| EP-3292129-B1 | LOW MOLECULAR WEIGHT HALOGENATED PORPHYRINE CARBOXAMIDE CHLORIN AND BACTERIOCHLORIN DERIVATIVES FOR USE IN PHOTODYNAMIC THERAPY FOR TREATING CANCER | LUZITIN S A (PT) | 2019-03-27 | — | — | EP | disclosed |
| US-20180282344-A1 | LOW MOLECULAR WEIGHT DERIVATIVES OF CARBOXAMIDE HALOGENATED PORPHYRINS, NAMELY CHLORINS AND BACTERIOCHLORINS, AND THEIR APPLICATIONS THEREOF | LUZITIN, S.A. (PT) | 2018-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450322-B2 | Low molecular weight derivatives of carboxamide halogenated porphyrins, namely chlorins and bacteriochlorins, and their applications thereof | CRY1, PPIA, PPOX | STAT3 361/4885STAT1 833/4885TOP1 1536/4885 |
| US-20180282344-A1 | LOW MOLECULAR WEIGHT DERIVATIVES OF CARBOXAMIDE HALOGENATED PORPHYRINS, NAMELY CHLORINS AND BACTERIOCHLORINS, AND THEIR APPLICATIONS THEREOF | CRY1, PPIA, PPOX | STAT3 361/4885STAT1 833/4885TOP1 1536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.