Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 3/20 | 0.34 |
| ▸ | CYCS | P99999 | 3/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20843716 | 0.89 | STAT3 (0.39) | STAT3STAT1ABCG2 | |
| SCHEMBL20520187 | 0.87 | STAT3 (0.46) | STAT3STAT1ABCG2TOP1CYCS | |
| SCHEMBL20843715 | 0.85 | ABCG2 (0.32) | STAT3STAT1ABCG2TOP1CYCS | |
| SCHEMBL20520075 | 0.82 | STAT3 (0.59) | STAT3STAT1TOP1TERTDHODH | |
| SCHEMBL20843735 | 0.81 | STAT3 (0.36) | STAT3STAT1ABCG2CYCS | |
| SCHEMBL28539046 | 0.79 | STAT3 (0.50) | STAT3STAT1TOP1CYCSTERT | |
| SCHEMBL28539011 | 0.76 | STAT3 (0.43) | STAT3STAT1TOP1TERT | |
| SCHEMBL8977875 | 0.73 | STAT3 (0.69) | STAT3STAT1ABCG2TOP1CYCS | |
| SCHEMBL21498219 | 0.73 | MAOB (0.32) | DHODH | |
| SCHEMBL30426808 | 0.73 | STAT3 (0.56) | STAT3STAT1TOP1CYCSTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450322-B2 | Low molecular weight derivatives of carboxamide halogenated porphyrins, namely chlorins and bacteriochlorins, and their applications thereof | LUZITIN, S.A. (PT) | 2019-10-22 | — | — | US | disclosed |
| EP-3292129-B1 | LOW MOLECULAR WEIGHT HALOGENATED PORPHYRINE CARBOXAMIDE CHLORIN AND BACTERIOCHLORIN DERIVATIVES FOR USE IN PHOTODYNAMIC THERAPY FOR TREATING CANCER | LUZITIN S A (PT) | 2019-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450322-B2 | Low molecular weight derivatives of carboxamide halogenated porphyrins, namely chlorins and bacteriochlorins, and their applications thereof | CRY1, PPIA, PPOX | STAT3 361/4885STAT1 833/4885ABCG2 3063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.