SCHEMBL20520330

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10788672	0.79	SIRT3 (0.51)	MTNR1ANOS1CYP1A2CYP2C19CYP2E1
	SCHEMBL14609418	0.79	ICAM1 (0.41)	CA12CA1CA2CA9TSPO
	SCHEMBL34462738	0.78	TAAR1 (0.56)	CA12CA1CA2CA9NOS3
	SCHEMBL2437293	0.77	TAAR1 (0.59)	CA12CA1CA2CA9MTNR1A
	SCHEMBL31689751	0.77	TAAR1 (0.59)	CA12CA1CA2CA9MTNR1A
	SCHEMBL19049440	0.76	MTNR1A (0.64)	MTNR1AMEN1KMT2A
	SCHEMBL91395	0.76	CA12 (0.50)	CA12CA1CA2CA9TSPO
	SCHEMBL10793655	0.76	ROCK2 (0.38)	CA12CA1CA2CA9CYP1A2
	SCHEMBL31444905	0.76	HSD17B10 (0.54)	CA12CA1CA2CA9TSPO
	SCHEMBL25493809	0.76	MAPK1 (0.47)	TSPOOPRK1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.