SCHEMBL20522339

SCHEMBL20522339

O=S(=O)(Nc1ccc(B(O)O)cc1)c1ccc(F)cc1

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.63
CA2 P00918 1/20 0.63
POLB P06746 2/20 0.60
ALDH1A1 P00352 5/20 0.58
MAPK1 P28482 2/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2C9 P11712 1/20 0.58
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
PKM P14618 2/20 0.55
MAPT P10636 2/20 0.55
FFAR1 O14842 2/20 0.55
FFAR4 Q5NUL3 2/20 0.55
HSD17B3 P37058 1/20 0.54
HSD17B2 P37059 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15208748 1.00 CA1 (0.63) CA1CA2POLBALDH1A1MAPK1
SCHEMBL28352311 0.93 CA1 (0.59) CA1CA2POLBALDH1A1MAPK1
SCHEMBL7501950 0.86 CA1 (0.81) CA1CA2POLBALDH1A1MAPK1
Hydrochloric Acid SCHEMBL5797806 0.84 CA1 (0.79) CA1CA2POLBALDH1A1MAPK1
SCHEMBL21530732 0.83 MAPT (0.62) CA1CA2POLBALDH1A1MAPK1
SCHEMBL12260977 0.83 MAPT (0.62) CA1CA2POLBALDH1A1MAPK1
SCHEMBL28632297 0.81 L3MBTL1 (0.58) CA1CA2ALDH1A1MEN1KMT2A
SCHEMBL7181976 0.81 CA1 (0.69) CA1CA2POLBALDH1A1MAPK1
SCHEMBL2568291 0.80 ALDH1A1 (0.74) CA1CA2POLBALDH1A1MAPK1
SCHEMBL28352310 0.80 CA1 (0.55) CA1CA2POLBALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001873-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2026-01-01 US disclosed
US-12384772-B2 Inhibitors VIVORYON THERAPEUTICS N.V. (DE) 2025-08-12 US disclosed
CN-117024352-A Novel inhibitors 维沃里翁治疗股份有限公司 2023-11-10 CN disclosed
US-20220274977-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2022-09-01 US disclosed
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 US disclosed
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 US disclosed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 US disclosed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 US disclosed
EP-3601269-A1 NOVEL INHIBITORS Probiodrug AG (DE) 2020-02-05 EP disclosed
WO-2018178384-A1 NOVEL INHIBITORS PROBIODRUG AG (DE) 2018-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001873-A1 NOVEL INHIBITORS GLS, GLS2, SULT1E1 CA1 2172/4885CA2 253/4885POLB 1502/4885
US-20200377493-A1 NOVEL INHIBITORS GLUL, GLS, QPCT CA1 3022/4885CA2 642/4885POLB 1286/4885
US-11339152-B2 Inhibitors GLUL, QPCT, GLS CA1 3098/4885CA2 724/4885POLB 1251/4885
US-12384772-B2 Inhibitors GLS, QPCT, GLS2 CA1 3839/4885CA2 620/4885POLB 927/4885
US-20220274977-A1 NOVEL INHIBITORS GLUL, GLS, QPCT CA1 2708/4885CA2 728/4885POLB 1457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.