SCHEMBL20522367

SCHEMBL20522367

c1ccc(Oc2ccc(-c3ccccc3NCc3ccc4[nH]cnc4c3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
QPCTL Q9NXS2 2/20 0.45
QPCT Q16769 3/20 0.39
KDR P35968 2/20 0.39
KDM4C Q9H3R0 1/20 0.37
ACP1 P24666 2/20 0.36
CACNA1B Q00975 2/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
MAOA P21397 1/20 0.36
ADRA1D P25100 1/20 0.36
MAOB P27338 1/20 0.36
ADRA1A P35348 1/20 0.36
FFAR1 O14842 1/20 0.35
GSTP1 P09211 1/20 0.35
CYP19A1 P11511 1/20 0.35
P2RY14 Q15391 1/20 0.35
BTK Q06187 1/20 0.35
LTA4H P09960 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29551444 1.00 QPCTL (0.45) QPCTLQPCTKDRKDM4CACP1
SCHEMBL29550590 0.89 ACP1 (0.46) QPCTLQPCTKDRACP1
SCHEMBL22712388 0.89 ACP1 (0.46) QPCTLQPCTKDRACP1
SCHEMBL20522355 0.86 KDR (0.38) QPCTLQPCTKDRKDM4CACP1
SCHEMBL29550890 0.86 QPCT (0.41) QPCTLQPCTKDRP2RY14
SCHEMBL20522272 0.86 QPCT (0.41) QPCTLQPCTKDRP2RY14
SCHEMBL29550390 0.86 KDR (0.38) QPCTLQPCTKDRKDM4CACP1
SCHEMBL20522432 0.85 QPCT (0.47) QPCTLQPCTKDR
SCHEMBL29550580 0.85 QPCT (0.47) QPCTLQPCTKDR
SCHEMBL20522441 0.84 ALDH1A1 (0.38) QPCTKDRADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 US claimed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 US claimed
EP-3601269-A1 NOVEL INHIBITORS Probiodrug AG (DE) 2020-02-05 EP claimed
WO-2018178384-A1 NOVEL INHIBITORS PROBIODRUG AG (DE) 2018-10-04 WO claimed
US-20260001873-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2026-01-01 US disclosed
US-12384772-B2 Inhibitors VIVORYON THERAPEUTICS N.V. (DE) 2025-08-12 US disclosed
US-20220274977-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2022-09-01 US disclosed
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 US disclosed
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 US disclosed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 US disclosed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 US disclosed
EP-3601269-A1 NOVEL INHIBITORS Probiodrug AG (DE) 2020-02-05 EP disclosed
WO-2018178384-A1 NOVEL INHIBITORS PROBIODRUG AG (DE) 2018-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001873-A1 NOVEL INHIBITORS GLS, GLS2, SULT1E1 QPCTL 60/4885QPCT 6/4885KDR 2611/4885
US-20200377493-A1 NOVEL INHIBITORS GLUL, GLS, QPCT QPCTL 7/4885QPCT 3/4885KDR 2432/4885
US-11339152-B2 Inhibitors GLUL, QPCT, GLS QPCTL 7/4885QPCT 2/4885KDR 2483/4885
US-12384772-B2 Inhibitors GLS, QPCT, GLS2 QPCTL 8/4885QPCT 2/4885KDR 2197/4885
US-20220274977-A1 NOVEL INHIBITORS GLUL, GLS, QPCT QPCTL 8/4885QPCT 3/4885KDR 2829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.