SCHEMBL20522371

SCHEMBL20522371

CC(=O)Nc1nnc(-c2ccc(Nc3ccccc3-c3ccc(Oc4ccccc4)cc3)cc2)s1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 3/20 0.51
CSNK2A1 P68400 3/20 0.51
RAB9A P51151 10/20 0.48
NPC1 O15118 8/20 0.48
KDM4E B2RXH2 4/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
ALDH1A1 P00352 2/20 0.48
TP53 P04637 1/20 0.48
CYP1A2 P05177 1/20 0.48
HPGD P15428 1/20 0.48
AHR P35869 1/20 0.48
HSD17B10 Q99714 1/20 0.48
HSP90AA1 P07900 1/20 0.47
HSP90AB1 P08238 1/20 0.47
DDX3X O00571 2/20 0.46
KMT2A Q03164 5/20 0.46
MEN1 O00255 4/20 0.46
RXFP1 Q9HBX9 2/20 0.46
CSNK2B P67870 1/20 0.46
POLB P06746 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28348979 0.95 CSNK2A2 (0.47) CSNK2A2CSNK2A1RAB9ANPC1KDM4E
SCHEMBL20522282 0.91 RAB9A (0.57) CSNK2A2CSNK2A1RAB9ANPC1KDM4E
SCHEMBL20522356 0.88 RAB9A (0.47) CSNK2A2CSNK2A1RAB9ANPC1KDM4E
SCHEMBL22712386 0.86 XIAP (0.53) CSNK2A2CSNK2A1RAB9ANPC1KDM4E
SCHEMBL28348731 0.86 RAB9A (0.52) CSNK2A2CSNK2A1RAB9ANPC1KDM4E
SCHEMBL22712385 0.86 SMN1; SMN2 (0.53) CSNK2A2CSNK2A1RAB9ANPC1KDM4E
SCHEMBL28348977 0.84 HDAC1 (0.51) CSNK2A2CSNK2A1KDM4ESMN1; SMN2ALDH1A1
SCHEMBL28349052 0.84 NPC1 (0.43) CSNK2A2CSNK2A1RAB9ANPC1KDM4E
SCHEMBL28352627 0.82 XIAP (0.49) CSNK2A2CSNK2A1RAB9ANPC1KDM4E
SCHEMBL20522354 0.82 KDM4E (0.57) CSNK2A2CSNK2A1RAB9ANPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001873-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2026-01-01 US disclosed
US-12384772-B2 Inhibitors VIVORYON THERAPEUTICS N.V. (DE) 2025-08-12 US disclosed
CN-117024352-A Novel inhibitors 维沃里翁治疗股份有限公司 2023-11-10 CN disclosed
US-20220274977-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2022-09-01 US disclosed
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 US disclosed
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 US disclosed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 US disclosed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 US disclosed
EP-3601269-A1 NOVEL INHIBITORS Probiodrug AG (DE) 2020-02-05 EP disclosed
WO-2018178384-A1 NOVEL INHIBITORS PROBIODRUG AG (DE) 2018-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001873-A1 NOVEL INHIBITORS GLS, GLS2, SULT1E1 CSNK2A2 1475/4885CSNK2A1 1576/4885RAB9A 838/4885
US-20200377493-A1 NOVEL INHIBITORS GLUL, GLS, QPCT CSNK2A2 2574/4885CSNK2A1 2963/4885RAB9A 3346/4885
US-11339152-B2 Inhibitors GLUL, QPCT, GLS CSNK2A2 2981/4885CSNK2A1 3311/4885RAB9A 3332/4885
US-12384772-B2 Inhibitors GLS, QPCT, GLS2 CSNK2A2 1717/4885CSNK2A1 2297/4885RAB9A 1349/4885
US-20220274977-A1 NOVEL INHIBITORS GLUL, GLS, QPCT CSNK2A2 2943/4885CSNK2A1 3018/4885RAB9A 3514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.