Sugi Predict

Sugi Predict / Compounds / SCHEMBL205237

SCHEMBL205237

SCHEMBL205237

CC(C)(C)OC(=O)NC(CCO)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 7/20 0.50
▸ CTSS P25774 6/20 0.50
▸ MEN1 O00255 1/20 0.47
▸ GAA P10253 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ PPARA Q07869 7/20 0.47
▸ PPARG P37231 6/20 0.47
▸ CTSL P07711 1/20 0.47
▸ CTSB P07858 1/20 0.47
▸ ACE P12821 1/20 0.46
▸ PPARD Q03181 2/20 0.45
▸ CA1 P00915 1/20 0.45
▸ CA2 P00918 1/20 0.45
▸ CA7 P43166 1/20 0.45
▸ IDO1 P14902 1/20 0.43
▸ ITGB3 P05106 1/20 0.43
▸ ITGA2B P08514 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2781378 1.00 CTSK (0.50) CTSKCTSSMEN1GAAKMT2A
SCHEMBL1423262 1.00 CTSK (0.50) CTSKCTSSMEN1GAAKMT2A
SCHEMBL11276177 0.98 CTSK (0.49) CTSKCTSSMEN1GAAKMT2A
SCHEMBL13571115 0.98 CTSK (0.49) CTSKCTSSMEN1GAAKMT2A
SCHEMBL7306871 0.98 CTSK (0.49) CTSKCTSSMEN1GAAKMT2A
Propylene Glycol SCHEMBL7982009 0.92 CTSK (0.45) CTSKCTSSMEN1GAAKMT2A
SCHEMBL3873210 0.91 CTSK (0.47) CTSKCTSSMEN1GAAKMT2A
SCHEMBL5285944 0.90 CTSK (0.52) CTSKCTSSMEN1GAAKMT2A
SCHEMBL4711467 0.90 CTSK (0.52) CTSKCTSSMEN1GAAKMT2A
SCHEMBL4024795 0.90 CTSK (0.52) CTSKCTSSMEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117106189-A Metal organic framework artificial hydrolase and preparation method and application thereof 华南理工大学 2023-11-24 — — CN claimed
EP-4688789-A1 MACROCYCLIC RAS INHIBITORS Revolution Medicines, Inc. (US) 2026-02-11 — — EP disclosed
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 — — US disclosed
US-20260001889-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS INC (US) 2026-01-01 — — US disclosed
US-12384797-B2 Thioeno[3,2-b] pyridin-7-amine compounds for treating familial dysautonomia PTC THERAPEUTICS, INC. (US) 2025-08-12 — — US disclosed
EP-4522622-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-03-19 — — EP disclosed
WO-2024211663-A9 MACROCYCLIC RAS INHIBITORS Revolution Medicines, Inc. (US) 2025-01-30 — — WO disclosed
US-20240368136-A1 BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-11-07 — — US disclosed
WO-2024211663-A1 CONDENSED MACROCYCLIC COMPOUNDS AS RAS INHIBITORS Revolution Medicines, Inc. (US) 2024-10-10 — — WO disclosed
US-20240287138-A1 CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY MERCK SHARP & DOHME LLC 2024-08-29 — — US disclosed
WO-2001017992-A1 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 2001-03-15 — — WO disclosed
WO-1996030343-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 1996-10-03 — — WO disclosed
CN-1098408-A The heterocycle inhibitor of farnesyl-protein transferase BRISTOL MYERS SQIBB COMPANY (US) 1995-02-08 — — CN disclosed
WO-1992014706-A1 CYCLOPENTANE-DERIVED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS PFIZER LIMITED (GB) 1992-09-03 — — WO disclosed
CN-1017902-B PROCESS FOR THE PREPARATION OF NOVEL CEPHALOSPORIN DERIVATIVES MEIJI PHARMACEUTIAL LTD (JP) 1992-08-19 — — CN disclosed
EP-0153709-B1 NOVEL CEPHALOSPORIN DERIVATIVES MEIJI SEIKA KAISHA LTD. (JP) 1991-08-14 — — EP disclosed
CN-1032786-A N-acyl amino acid derivative and uses thereof BANYU PHARMA CO LTD (JP) 1989-05-10 — — CN disclosed
US-4785090-A ANTIBIOTICS, BACTERICIDES MEIJI SEIKA KAISHA, LTD. (JP) 1988-11-15 — — US disclosed
CN-85105120-A The preparation method of novel cephalosporin derivatives — 1986-12-31 — — CN disclosed
EP-0153709-A2 Novel cephalosporin derivatives MEIJI SEIKA KAISHA LTD. (JP) 1985-09-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001889-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SF3B1, SF3A1, SF3B5 CTSK 4670/4885CTSS 4634/4885MEN1 4113/4885
US-20240287138-A1 CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY TNF, TNFRSF1A, CD40 CTSK 800/4885CTSS 1755/4885MEN1 3591/4885
US-20240368136-A1 BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS MAPK1, ALK, MAP3K1 CTSK 3049/4885CTSS 3952/4885MEN1 1634/4885
US-12384797-B2 Thioeno[3,2-b] pyridin-7-amine compounds for treating familial dysautonomia SF3B5, SF3B2, SF3B1 CTSK 4597/4885CTSS 4459/4885MEN1 1230/4885
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP3, DPP7, DPP9 CTSK 82/4885CTSS 265/4885MEN1 3217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.