SCHEMBL20524864

SCHEMBL20524864

NCC1CCC(C(=O)N2CCN(c3ccncc3)CC2)CC1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 6/20 0.57
ITGA2B P08514 6/20 0.57
TDP1 Q9NUW8 1/20 0.56
LSS P48449 2/20 0.53
CHRM1 P11229 5/20 0.49
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7788456 0.86 ITGB3 (0.61) ITGB3ITGA2BTDP1LSSCHRM1
SCHEMBL23138610 0.84 ITGB3 (0.54) ITGB3ITGA2BTDP1LSSCHRM1
SCHEMBL4721763 0.82 F10 (0.56) ITGB3ITGA2BLSS
SCHEMBL4721163 0.82 F10 (0.56) ITGB3ITGA2BLSS
SCHEMBL26706322 0.82 ALDH1A1 (0.59) ITGB3ITGA2BTDP1LSSCHRM1
SCHEMBL23116669 0.81 ITGB3 (0.53) ITGB3ITGA2BTDP1LSSCHRM1
SCHEMBL23116667 0.81 ITGB3 (0.53) ITGB3ITGA2BTDP1LSSCHRM1
SCHEMBL6791781 0.80 ITGB3 (0.57) ITGB3ITGA2BTDP1LSSCHRM1
SCHEMBL1668332 0.80 LMNA (0.57) TDP1MEN1ALDH1A1KMT2A
SCHEMBL11893729 0.80 LMNA (0.57) TDP1MEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630512-B2 Agents for differentiating stem cells and treating cancer MINERVA BIOTECHNOLOGIES CORPORATION (US) 2026-05-19 US disclosed
EP-3600451-B1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORP (US) 2025-12-24 EP disclosed
US-12202799-B2 Agents for differentiating stem cells and treating cancer MINERVA BIOTECHNOLOGIES CORPORATION (US) 2025-01-21 US disclosed
US-20240409515-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORPORATION 2024-12-12 US disclosed
US-20220242823-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORPORATION 2022-08-04 US disclosed
US-20220242823-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORPORATION 2022-08-04 US disclosed
US-20210299109-A1 AGENTS FOR TREATING CANCER AND METHODS FOR IDENTIFYING SAID AGENTS MINERVA BIOTECHNOLOGIES CORPORATION 2021-09-30 US disclosed
US-20210299109-A1 AGENTS FOR TREATING CANCER AND METHODS FOR IDENTIFYING SAID AGENTS MINERVA BIOTECHNOLOGIES CORPORATION 2021-09-30 US disclosed
US-20210087143-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORP (US) 2021-03-25 US disclosed
EP-3600451-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER Minerva Biotechnologies Corporation (US) 2020-02-05 EP disclosed
WO-2018183654-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORPORATION (US) 2018-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210299109-A1 AGENTS FOR TREATING CANCER AND METHODS FOR IDENTIFYING SAID AGENTS MCL1, CD44, EPCAM ITGB3 618/4885ITGA2B 1034/4885TDP1 2734/4885
US-12202799-B2 Agents for differentiating stem cells and treating cancer MCL1, CD44, CRABP2 ITGB3 315/4885ITGA2B 552/4885TDP1 2950/4885
US-20210087143-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MCL1, CD44, CRABP2 ITGB3 315/4885ITGA2B 552/4885TDP1 2950/4885
US-12630512-B2 Agents for differentiating stem cells and treating cancer MCL1, POU2F1, NES ITGB3 446/4885ITGA2B 1547/4885TDP1 3918/4885
US-20240409515-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MCL1, CD44, CRABP2 ITGB3 315/4885ITGA2B 552/4885TDP1 2950/4885
US-20220242823-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MCL1, CD44, CRABP2 ITGB3 315/4885ITGA2B 552/4885TDP1 2950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.