Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 18/20 | 0.43 |
| ▸ | AXL | P30530 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20525637 | 0.85 | LMNA (0.44) | METAXL | |
| SCHEMBL15404764 | 0.85 | AXL (0.54) | METAXLKDR | |
| SCHEMBL20525560 | 0.85 | LMNA (0.44) | METAXL | |
| SCHEMBL371800 | 0.84 | MET (0.59) | METAXLKDR | |
| SCHEMBL20525677 | 0.80 | MET (0.46) | METKDR | |
| SCHEMBL15404759 | 0.78 | MET (0.43) | METKDR | |
| SCHEMBL20525830 | 0.78 | MET (0.52) | METKDR | |
| SCHEMBL15404803 | 0.77 | MET (0.42) | METKDR | |
| SCHEMBL15405214 | 0.77 | MET (0.39) | METKDR | |
| SCHEMBL15405168 | 0.77 | MET (0.41) | METKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2101759-B1 | METHODS OF USING MEK INHIBITORS | EXELIXIS INC (US) | 2018-10-10 | — | — | EP | claimed |