Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 9/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20525560 | 0.97 | LMNA (0.44) | LMNAHPGDTSHRMETPDE10A | |
| SCHEMBL20525618 | 0.85 | MET (0.43) | METAXL | |
| SCHEMBL371815 | 0.84 | MET (0.56) | METAXL | |
| SCHEMBL371607 | 0.82 | MET (0.57) | METAXL | |
| SCHEMBL20216670 | 0.80 | MET (0.49) | METAXL | |
| SCHEMBL20525677 | 0.79 | MET (0.46) | MET | |
| SCHEMBL15404759 | 0.79 | MET (0.43) | MET | |
| SCHEMBL8324767 | 0.79 | HPGD (0.63) | LMNAHPGDTSHRPDE10AMAPT | |
| SCHEMBL29741392 | 0.79 | HPGD (0.63) | LMNAHPGDTSHRPDE10AMAPT | |
| SCHEMBL15426783 | 0.78 | MET (0.47) | LMNAHPGDTSHRMETAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2101759-B1 | METHODS OF USING MEK INHIBITORS | EXELIXIS INC (US) | 2018-10-10 | — | — | EP | claimed |