Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900510 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1TDP1PTPN1PTPRZ1 | |
| SCHEMBL5365562 | 0.79 | — | — | |
| SCHEMBL900704 | 0.77 | KDM4E (0.35) | KDM4EALDH1A1TDP1PTPN1PTPRZ1 | |
| SCHEMBL900778 | 0.77 | KDM4E (0.35) | KDM4EALDH1A1TDP1PTPN1PTPRZ1 | |
| SCHEMBL102848 | 0.77 | CES2 (0.40) | ALDH1A1 | |
| SCHEMBL23174652 | 0.74 | CES2 (0.39) | ALDH1A1 | |
| SCHEMBL29121446 | 0.74 | CES2 (0.39) | ALDH1A1 | |
| SCHEMBL28642337 | 0.74 | CES2 (0.39) | ALDH1A1 | |
| SCHEMBL27886103 | 0.74 | CES2 (0.39) | ALDH1A1 | |
| SCHEMBL28401871 | 0.71 | KDM4E (0.33) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368064-B | 1,2, 3-triazole derivative and insecticide and acaricide comprising the same as active ingredient | 北兴化学工业株式会社 | 2022-04-26 | — | — | CN | disclosed |
| US-20210403462-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-12-30 | — | — | US | disclosed |
| EP-3877380-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-09-15 | — | — | EP | disclosed |
| US-11046659-B2 | 1,2,3-triazole derivative and insecticide and acaricide containing said derivative as active ingredient | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-06-29 | — | — | US | disclosed |
| US-20190322630-A1 | 1,2,3-TRIAZOLE DERIVATIVE AND INSECTICIDE AND ACARICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-10-24 | — | — | US | disclosed |
| US-10377737-B2 | 1,2,3-triazole derivative and insecticide and acaricide containing said derivative as active ingredient | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-08-13 | — | — | US | disclosed |
| US-20180290986-A1 | 1,2,3-TRIAZOLE DERIVATIVE AND INSECTICIDE AND ACARICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2018-10-11 | — | — | US | disclosed |
| EP-3385254-A1 | 1,2,3-TRIAZOLE DERIVATIVE AND INSECTICIDE/ACARICIDE HAVING SAID DERIVATIVE AS ACTIVE INGREDIENT | Hokko Chemical Industry Co., Ltd. (JP) | 2018-10-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180290986-A1 | 1,2,3-TRIAZOLE DERIVATIVE AND INSECTICIDE AND ACARICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | AADAC, CYP51A1, NAT1 | KDM4E 1111/4885ALDH1A1 89/4885TDP1 1095/4885 |
| US-10377737-B2 | 1,2,3-triazole derivative and insecticide and acaricide containing said derivative as active ingredient | AADAC, CYP51A1, NAT1 | KDM4E 1111/4885ALDH1A1 89/4885TDP1 1095/4885 |
| US-11046659-B2 | 1,2,3-triazole derivative and insecticide and acaricide containing said derivative as active ingredient | AADAC, CYP51A1, NAT1 | KDM4E 1111/4885ALDH1A1 89/4885TDP1 1095/4885 |
| US-20210403462-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | DDT, ACHE, NIT2 | KDM4E 2022/4885ALDH1A1 1091/4885TDP1 1796/4885 |
| US-20190322630-A1 | 1,2,3-TRIAZOLE DERIVATIVE AND INSECTICIDE AND ACARICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | AADAC, CYP51A1, NAT1 | KDM4E 1111/4885ALDH1A1 89/4885TDP1 1095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.