SCHEMBL23174652

SCHEMBL23174652

FC(F)(F)c1c[c]cc(C(F)(F)F)c1.[GaH3]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.39
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
IDO1 P14902 2/20 0.34
MAPK1 P28482 1/20 0.32
ADRB1 P08588 1/20 0.31
HTR3E A5X5Y0 2/20 0.30
HTR3B O95264 2/20 0.30
HTR3A P46098 2/20 0.30
HTR3D Q70Z44 2/20 0.30
HTR3C Q8WXA8 2/20 0.30
MAPT P10636 1/20 0.30
RAPGEF4 Q8WZA2 1/20 0.30
ITGB3 P05106 1/20 0.30
ITGAV P06756 1/20 0.30
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30
PTPN5 P54829 1/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL102848 0.97 CES2 (0.40) CES2TSHRALDH1A1IDO1MAPK1
SCHEMBL27886103 0.94 CES2 (0.39) CES2TSHRALDH1A1IDO1MAPK1
SCHEMBL28642337 0.94 CES2 (0.39) CES2TSHRALDH1A1IDO1MAPK1
SCHEMBL29121446 0.94 CES2 (0.39) CES2TSHRALDH1A1IDO1MAPK1
SCHEMBL28585089 0.87 CES2 (0.34) CES2TSHRALDH1A1IDO1HTR3E
Magnesium Chloride Anhydrous SCHEMBL29163555 0.87 CES2 (0.34) CES2TSHRALDH1A1IDO1
SCHEMBL2879163 0.85 KIF11 (0.38) CES2IDO1MAPTRAPGEF4KIF11
SCHEMBL147083 0.81 AHR (0.36) CES2TSHRALDH1A1MAPTRAPGEF4
SCHEMBL27573 0.81 ALDH1A1 (0.31) CES2TSHRALDH1A1
SCHEMBL596022 0.81 RAPGEF4 (0.35) CES2TSHRALDH1A1MAPTRAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115703939-A Curable composition, cured product, cured film, display panel, and method for producing cured film 东京应化工业株式会社 2023-02-17 CN disclosed
CN-114675489-A Curable resin composition, cured product thereof, method for producing cured film, and method for producing microlens 东京应化工业株式会社 2022-06-28 CN disclosed
CN-114502613-A Curable composition, cured product, and method for forming cured product 东京应化工业株式会社 2022-05-13 CN disclosed
WO-2021065796-A1 CURABLE COMPOSITION, CURED MATERIAL, AND METHOD FOR FORMING CURED MATERIAL 東京応化工業株式会社 2021-04-08 WO disclosed