SCHEMBL20528161

SCHEMBL20528161

FC(F)(F)C(F)(F)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9588690 1.00 LMNA (0.38) LMNATHRB
SCHEMBL31156972 1.00 LMNA (0.38) LMNATHRB
SCHEMBL1095729 0.97 LMNA (0.33) LMNA
SCHEMBL11511027 0.94 LMNA (0.42) LMNATHRB
SCHEMBL9589771 0.94 LMNA (0.42) LMNATHRB
SCHEMBL3313899 0.94 LMNA (0.42) LMNATHRB
SCHEMBL21355 0.94 LMNA (0.42) LMNATHRB
SCHEMBL3629816 0.94 LMNA (0.42) LMNATHRB
SCHEMBL11509926 0.94 LMNA (0.42) LMNATHRB
SCHEMBL7153944 0.94 LMNA (0.42) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10399916-B2 Method of producing hydrofluoroolefin AGC Inc. (JP) 2019-09-03 US claimed
EP-3392229-A1 METHOD FOR PRODUCING HYDROFLUOROOLEFIN AGC Inc. (JP) 2018-10-24 EP claimed
US-20180290951-A1 METHOD OF PRODUCING HYDROFLUOROOLEFIN ASAHI GLASS COMPANY, LIMITED (JP) 2018-10-11 US claimed
CN-108430959-A Process for producing hydrofluoroolefin 旭硝子株式会社 2018-08-21 CN claimed
US-20230259044-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2023-08-17 US disclosed
US-10399916-B2 Method of producing hydrofluoroolefin AGC Inc. (JP) 2019-09-03 US disclosed
EP-3392229-A1 METHOD FOR PRODUCING HYDROFLUOROOLEFIN AGC Inc. (JP) 2018-10-24 EP disclosed
US-20180290951-A1 METHOD OF PRODUCING HYDROFLUOROOLEFIN ASAHI GLASS COMPANY, LIMITED (JP) 2018-10-11 US disclosed
CN-108430959-A Process for producing hydrofluoroolefin 旭硝子株式会社 2018-08-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10399916-B2 Method of producing hydrofluoroolefin HAO2, SFXN1, HAX1 LMNA 2929/4885THRB 2184/4885
US-20180290951-A1 METHOD OF PRODUCING HYDROFLUOROOLEFIN HAO2, SFXN1, HAX1 LMNA 2929/4885THRB 2184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.