Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20528319 | 0.91 | HDAC1 (0.42) | ACHEHDAC1HDAC2TDP1CHRM1 | |
| SCHEMBL721271 | 0.81 | HDAC1 (0.40) | HDAC1HDAC2TDP1CHRM1AKR1A1 | |
| SCHEMBL30145015 | 0.78 | HCAR2 (0.41) | HDAC1HDAC2TDP1CHRM1AKR1A1 | |
| SCHEMBL234643 | 0.77 | ALDH1A1 (0.54) | ACHETDP1TSHRCA1CA2 | |
| SCHEMBL28017335 | 0.77 | CA1 (0.50) | HDAC1HDAC2TDP1CHRM1AKR1A1 | |
| SCHEMBL27849382 | 0.77 | HDAC1 (0.55) | ACHEHDAC1HDAC2TDP1CHRM1 | |
| SCHEMBL821952 | 0.75 | ACHE (0.41) | ACHEHDAC1HDAC2TDP1CHRM1 | |
| SCHEMBL2531270 | 0.75 | ACHE (0.41) | ACHEHDAC1HDAC2TDP1CHRM1 | |
| SCHEMBL233234 | 0.74 | ALDH1A1 (0.56) | ACHETDP1TSHRCA1CA2 | |
| SCHEMBL15015736 | 0.73 | HDAC1 (0.43) | HDAC1HDAC2TDP1CHRM1AKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11286328-B2 | Thermoplastic polyurethane elastomer, and preparation method, use and product thereof | WANHUA CHEMICAL GROUP CO., LTD. | 2022-03-29 | — | — | US | disclosed |
| US-20180291141-A1 | THERMOPLASTIC POLYURETHANE ELASTOMER, AND PREPARATION METHOD, USE AND PRODUCT THEREOF | WANHUA CHEMICAL GROUP CO., LTD. (CN) | 2018-10-11 | — | — | US | disclosed |