Chavicol

Chavicol

SCHEMBL2052932

C=CCc1ccc(O)cc1.[KH]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ XDH P47989 1/20 0.56
▸ ALDH1A1 P00352 5/20 0.54
▸ GABRA1 P14867 3/20 0.54
▸ GABRB2 P47870 3/20 0.54
▸ MEN1 O00255 2/20 0.54
▸ GAA P10253 2/20 0.54
▸ MAPT P10636 2/20 0.54
▸ CNR1 P21554 2/20 0.54
▸ CNR2 P34972 2/20 0.54
▸ KMT2A Q03164 2/20 0.54
▸ KDM4E B2RXH2 2/20 0.54
▸ PPARG P37231 2/20 0.54
▸ PPARD Q03181 2/20 0.54
▸ ALDH2 P05091 1/20 0.54
▸ AKR1B1 P15121 1/20 0.54
▸ HPGD P15428 1/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.54
▸ CYP3A4 P08684 2/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ TP53 P04637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chavicol SCHEMBL30870 0.97 XDH (0.58) XDHALDH1A1GABRA1GABRB2MEN1
Chavicol SCHEMBL7187339 0.95 XDH (0.56) XDHALDH1A1GABRA1GABRB2MEN1
Chavicol SCHEMBL11043594 0.95 XDH (0.56) XDHALDH1A1GABRA1GABRB2MEN1
Chavicol SCHEMBL28830232 0.95 XDH (0.56) XDHALDH1A1GABRA1GABRB2MEN1
Chavicol SCHEMBL5483528 0.95 XDH (0.56) XDHALDH1A1GABRA1GABRB2MEN1
Chavicol SCHEMBL10902352 0.95 XDH (0.56) XDHALDH1A1GABRA1GABRB2MEN1
Chavicol SCHEMBL10565597 0.95 XDH (0.56) XDHALDH1A1GABRA1GABRB2MEN1
Chavicol SCHEMBL5489418 0.95 XDH (0.56) XDHALDH1A1GABRA1GABRB2MEN1
Chavicol SCHEMBL7924978 0.95 XDH (0.56) XDHALDH1A1GABRA1GABRB2MEN1
Chavicol SCHEMBL10511637 0.95 XDH (0.56) XDHALDH1A1GABRA1GABRB2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115038777-A Process for producing alkylsalicylic acids and overbased detergents derived therefrom 路博润公司 2022-09-09 — — CN disclosed
EP-2507353-B1 LOW TEMPERATURE PERFORMANCE LUBRICATING OIL DETERGENTS AND METHOD OF MAKING THE SAME CHEVRON ORONITE CO (US) 2019-06-12 — — EP disclosed
EP-2247700-B1 LOW TEMPERATURE PERFORMANCE LUBRICATING OIL DETERGENTS CHEVRON ORONITE CO (US) 2018-10-03 — — EP disclosed
US-9255043-B2 Liquid crude hydrocarbon composition CHEVRON ORONITE COMPANY LLC (US) 2016-02-09 — — US disclosed
US-8993499-B2 Low temperature performance lubricating oil detergents and method of making the same CHEVRON ORONITE COMPANY LLC (US) 2015-03-31 — — US disclosed
US-8778856-B2 Low temperature performance lubricating oil detergents and method of making the same CHEVRON ORONITE COMPANY LLC (US) 2014-07-15 — — US disclosed
EP-2751218-A1 LIQUID CRUDE HYDROCARBON COMPOSITION Chevron Oronite Company LLC (US) 2014-07-09 — — EP disclosed
WO-2013032579-A1 LIQUID CRUDE HYDROCARBON COMPOSITION CHEVRON ORONITE COMPANY LLC (US) 2013-03-07 — — WO disclosed
US-20130048079-A1 Liquid crude hydrocarbon composition CHEVRON ORONITE COMPANY LLC 2013-02-28 — — US disclosed
EP-2507353-A2 LOW TEMPERATURE PERFORMANCE LUBRICATING OIL DETERGENTS AND METHOD OF MAKING THE SAME Chevron Oronite Company LLC (US) 2012-10-10 — — EP disclosed
WO-2011068733-A2 LOW TEMPERATURE PERFORMANCE LUBRICATING OIL DETERGENTS AND METHOD OF MAKING THE SAME CHEVRON ORONITE COMPANY LLC (US) 2011-06-09 — — WO disclosed
US-20110130315-A1 LOW TEMPERATURE PERFORMANCE LUBRICATING OIL DETERGENTS AND METHOD OF MAKING THE SAME CHEVRON ORONITE COMPANY LLC 2011-06-02 — — US disclosed
EP-2247700-A2 LOW TEMPERATURE PERFORMANCE LUBRICATING OIL DETERGENTS AND METHOD OF MAKING THE SAME Chevron Oronite Company LLC (US) 2010-11-10 — — EP disclosed
WO-2009086140-A2 LOW TEMPERATURE PERFORMANCE LUBRICATING OIL DETERGENTS AND METHOD OF MAKING THE SAME CHEVRON ORONITE COMPANY LLC (US) 2009-07-09 — — WO disclosed
US-20090170737-A1 LOW TEMPERATURE PERFORMANCE LUBRICATING OIL DETERGENTS AND METHOD OF MAKING THE SAME Chevron Oronite LLC 2009-07-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170737-A1 LOW TEMPERATURE PERFORMANCE LUBRICATING OIL DETERGENTS AND METHOD OF MAKING THE SAME DEGS1, HSD17B12, HSD17B1 XDH 2441/4885ALDH1A1 891/4885GABRA1 2194/4885
US-20110130315-A1 LOW TEMPERATURE PERFORMANCE LUBRICATING OIL DETERGENTS AND METHOD OF MAKING THE SAME DEGS1, DGAT1, DHCR7 XDH 3333/4885ALDH1A1 1838/4885GABRA1 3088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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