Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | VDR | P11473 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28432943 | 0.80 | SLC6A3 (0.50) | KDM4EALDH1A1SMN1; SMN2SLC6A3SLC6A4 | |
| SCHEMBL6437163 | 0.79 | SLC6A3 (0.59) | KDM4EALDH1A1SMN1; SMN2SLC6A3SLC6A4 | |
| SCHEMBL27029841 | 0.78 | KMT2A (0.51) | KDM4EALDH1A1SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL28699403 | 0.76 | XDH (0.47) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL403150 | 0.76 | ALDH1A1 (0.63) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23272100 | 0.76 | ALDH1A1 (0.47) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3228101 | 0.75 | ALDH1A1 (0.62) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1586163 | 0.75 | SLC6A3 (0.54) | KDM4EALDH1A1RAB9ASLC6A3SLC6A4 | |
| SCHEMBL30816561 | 0.73 | ALDH1A1 (0.44) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10533851 | 0.73 | SLC6A3 (0.65) | ALDH1A1NPC1RAB9ASLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018187294-A1 | PYRIMIDO-PYRIDAZINONE COMPOUND COMBINATIONS, METHODS, KITS AND FORMULATIONS THEREOF | ASANA BIOSCIENCES, LLC (US) | 2018-10-11 | — | — | WO | disclosed |