Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 16/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20530307 | 0.93 | MET (0.38) | METPARP1 | |
| SCHEMBL20530371 | 0.89 | MET (0.43) | METPDE2APDE10APARP1 | |
| SCHEMBL22729930 | 0.87 | MET (0.36) | METCDKL5 | |
| SCHEMBL1330437 | 0.84 | MET (0.54) | MET | |
| Hydrochloric Acid SCHEMBL1328254 | 0.83 | MET (0.54) | MET | |
| SCHEMBL1330827 | 0.83 | MET (0.50) | MET | |
| SCHEMBL20530291 | 0.83 | PARP1 (0.38) | METPDE10APARP1 | |
| Hydrochloric Acid SCHEMBL1331583 | 0.83 | MET (0.49) | MET | |
| SCHEMBL20530344 | 0.82 | GPR119 (0.38) | MET | |
| SCHEMBL22729934 | 0.82 | MET (0.37) | METPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571878-B1 | NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B]PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES | INCOZEN THERAPEUTICS PVT LTD (IN) | 2018-10-17 | — | — | EP | claimed |