Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 7/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.35 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2051449 | 0.80 | AAK1 (0.35) | MAPK14AAK1 | |
| SCHEMBL27894349 | 0.78 | TGFBR1 (0.33) | TGFBR1MAPK14 | |
| SCHEMBL2050524 | 0.77 | BRAF (0.36) | MAPK14AAK1 | |
| SCHEMBL27894271 | 0.75 | — | — | |
| SCHEMBL2053630 | 0.73 | AAK1 (0.42) | MAPK14AAK1 | |
| SCHEMBL2050761 | 0.73 | TRPV3 (0.32) | — | |
| SCHEMBL2053773 | 0.72 | KMO (0.35) | MAPK14AAK1 | |
| SCHEMBL27894348 | 0.72 | MAPK14 (0.42) | MAPK14 | |
| SCHEMBL27894182 | 0.69 | S1PR1 (0.32) | — | |
| SCHEMBL2051412 | 0.68 | GRIN2B (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516423-A1 | THIENYLPYRI (MI) DINYLAZOLE AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI | Bayer CropScience AG (DE) | 2012-10-31 | — | — | EP | disclosed |
| CN-102762551-A | Thienylpyri (mi) dinylpyrazoles and their use for controlling phytopathogenic fungi | BAYER CROPSCIENCE AG | 2012-10-31 | — | — | CN | disclosed |
| US-20110237588-A1 | Thienylpyri(mi)dinylazole | BAYER CROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| WO-2011076725-A1 | THIENYLPYRI (MI) DINYLAZOLE AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI | BAYER CROPSCIENCE AG (DE) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237588-A1 | Thienylpyri(mi)dinylazole | PADI1, TH, H1-3 | TGFBR1 573/4885MAPK14 3753/4885AAK1 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.