Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.39 |
| ▸ | F11 | P03951 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | LPL | P06858 | 4/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30404549 | 0.88 | LIPG (0.51) | GSK3AGSK3BLIPGF11F2 | |
| SCHEMBL2049952 | 0.86 | F11 (0.40) | GSK3AGSK3BLIPGF11F2 | |
| SCHEMBL23599196 | 0.85 | DGAT1 (0.41) | GSK3AGSK3BLIPGLPLDGAT1 | |
| SCHEMBL28507924 | 0.81 | F11 (0.37) | GSK3AGSK3BLIPGF11F2 | |
| SCHEMBL16465738 | 0.80 | LPL (0.53) | GSK3AGSK3BLIPGLPLKDM4E | |
| SCHEMBL15984293 | 0.79 | LIPG (0.39) | GSK3AGSK3BLIPGF11LPL | |
| SCHEMBL29780491 | 0.77 | LIPG (0.37) | GSK3AGSK3BLIPGLPLPRMT5 | |
| SCHEMBL31227320 | 0.77 | LPL (0.44) | GSK3AGSK3BLIPGF11LPL | |
| SCHEMBL2458829 | 0.77 | LPL (0.44) | GSK3AGSK3BLIPGF11LPL | |
| SCHEMBL3476747 | 0.76 | HIF1A (0.40) | GSK3AGSK3BLIPGLPLDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516423-A1 | THIENYLPYRI (MI) DINYLAZOLE AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI | Bayer CropScience AG (DE) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011076725-A1 | THIENYLPYRI (MI) DINYLAZOLE AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI | BAYER CROPSCIENCE AG (DE) | 2011-06-30 | — | — | WO | disclosed |