Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.39 |
| ▸ | GRM6 | O15303 | 3/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.39 |
| ▸ | ARG1 | P05089 | 5/20 | 0.37 |
| ▸ | ARG2 | P78540 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20533656 | 1.00 | GRM2 (0.39) | GRM2GRM6GRM3ARG1ARG2 | |
| SCHEMBL11665887 | 0.81 | HSD11B1 (0.34) | EPHX1HSD11B1 | |
| SCHEMBL9666966 | 0.81 | GRM2 (0.42) | GRM2GRM6GRM3ARG1ARG2 | |
| SCHEMBL1532382 | 0.81 | GRM2 (0.42) | GRM2GRM6GRM3ARG1ARG2 | |
| SCHEMBL112520 | 0.79 | EPHX1 (0.37) | EPHX1HSD11B1 | |
| SCHEMBL27767356 | 0.79 | NPC1 (0.40) | — | |
| SCHEMBL29682105 | 0.76 | HSD11B1 (0.33) | EPHX1HSD11B1 | |
| SCHEMBL7978200 | 0.76 | HSD11B1 (0.33) | EPHX1HSD11B1 | |
| SCHEMBL29112277 | 0.76 | HSD11B1 (0.33) | EPHX1HSD11B1 | |
| SCHEMBL2159743 | 0.75 | HSD11B1 (0.33) | EPHX1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3628677-B1 | METHOD FOR PREPARING A CYCLOPEPTIDE | UNIV NAT TSING HUA (TW) | 2021-11-10 | — | — | EP | disclosed |
| EP-3392262-B1 | CYCLOPEPTIDE, PHARMACEUTICAL OR COSMETIC COMPOSITION COMPRISING THE SAME AND METHOD FOR PREPARING THE SAME | UNIV NAT TSING HUA (TW) | 2021-08-18 | — | — | EP | disclosed |
| US-10851134-B2 | Method for preparing cyclopeptide | NATIONAL TSING HUA UNIVERSITY (TW) | 2020-12-01 | — | — | US | disclosed |
| US-20200339632-A1 | METHOD FOR PREPARING CYCLOPEPTIDE | NATIONAL TSING HUA UNIVERSITY | 2020-10-29 | — | — | US | disclosed |
| US-10745444-B2 | Cyclopeptide, pharmaceutical or cosmetic composition comprising the same and method for preparing the same | NATIONAL TSING HUA UNIVERSITY (TW) | 2020-08-18 | — | — | US | disclosed |
| EP-3628677-A1 | METHOD FOR PREPARING A CYCLOPEPTIDE | National Tsing Hua University (TW) | 2020-04-01 | — | — | EP | disclosed |
| EP-3392262-A1 | CYCLOPEPTIDE, PHARMACEUTICAL OR COSMETIC COMPOSITION COMPRISING THE SAME AND METHOD FOR PREPARING THE SAME | National Tsing Hua University (TW) | 2018-10-24 | — | — | EP | disclosed |
| US-20180298060-A1 | Cyclopeptide, pharmaceutical or cosmetic composition comprising the same and method for preparing the same | NATIONAL TSING HUA UNIVERSITY (TW) | 2018-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10851134-B2 | Method for preparing cyclopeptide | PPIB, PPIA, PPIL1 | GRM2 4497/4885GRM6 4171/4885GRM3 4463/4885 |
| US-10745444-B2 | Cyclopeptide, pharmaceutical or cosmetic composition comprising the same and method for preparing the same | PSAP, PPIG, PPIB | GRM2 4609/4885GRM6 4459/4885GRM3 4617/4885 |
| US-20200339632-A1 | METHOD FOR PREPARING CYCLOPEPTIDE | PPIB, PPIA, PPIL1 | GRM2 4497/4885GRM6 4171/4885GRM3 4463/4885 |
| US-20180298060-A1 | Cyclopeptide, pharmaceutical or cosmetic composition comprising the same and method for preparing the same | PSAP, PPIG, PPIB | GRM2 4609/4885GRM6 4459/4885GRM3 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.