SCHEMBL27767356

SCHEMBL27767356

CC1CCC(C(C)C)C(N)(C(=O)c2ccccc2)C1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TRPM8 Q7Z2W7 2/20 0.39
LMNA P02545 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ACHE P22303 1/20 0.37
TRPV1 Q8NER1 1/20 0.34
CCR2 P41597 1/20 0.34
SLC6A2 P23975 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7799804 0.83 L3MBTL1 (0.42) NPC1L3MBTL1TRPM8LMNAMEN1
SCHEMBL20533654 0.79 GRM2 (0.39)
SCHEMBL20533656 0.79 GRM2 (0.39)
SCHEMBL12484267 0.69 NPSR1 (0.43) LMNAMEN1KMT2ACCR2
SCHEMBL5244036 0.69 NPSR1 (0.43) LMNAMEN1KMT2ACCR2
SCHEMBL24540510 0.69 ALDH1A1 (0.41) NPC1L3MBTL1TRPM8LMNAMEN1
SCHEMBL29112517 0.69 ALDH1A1 (0.41) NPC1L3MBTL1TRPM8LMNAMEN1
SCHEMBL29112515 0.69 ALDH1A1 (0.41) NPC1L3MBTL1TRPM8LMNAMEN1
SCHEMBL337275 0.68 CCR2 (0.36) MEN1KMT2ACCR2SLC6A2
SCHEMBL7978200 0.67 HSD11B1 (0.33) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101422229-A Romatic neomenthylamides as flavouring agents SYMRISE GMBH & CO KG (DE) 2009-05-06 CN claimed
CN-101422229-A Romatic neomenthylamides as flavouring agents SYMRISE GMBH & CO KG (DE) 2009-05-06 CN disclosed