Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10611673 | 0.84 | MAPK1 (0.56) | KMT2AMAPK1ALDH1A1L3MBTL1GAA | |
| SCHEMBL3370446 | 0.83 | KMT2A (0.58) | KMT2AMAPK1ALDH1A1L3MBTL1GAA | |
| SCHEMBL14920646 | 0.80 | KMT2A (0.56) | KMT2AMAPK1ALDH1A1L3MBTL1GAA | |
| SCHEMBL29858300 | 0.80 | MAPK1 (0.50) | KMT2AMAPK1ALDH1A1L3MBTL1GAA | |
| SCHEMBL28824727 | 0.80 | MAPK1 (0.50) | KMT2AMAPK1ALDH1A1L3MBTL1GAA | |
| SCHEMBL6017272 | 0.79 | MAPK1 (0.52) | KMT2AMAPK1ALDH1A1L3MBTL1GAA | |
| SCHEMBL9967732 | 0.79 | KMT2A (0.61) | KMT2AMAPK1ALDH1A1L3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL784570 | 0.78 | L3MBTL1 (0.59) | KMT2AMAPK1ALDH1A1L3MBTL1GAA | |
| SCHEMBL28895677 | 0.76 | KMT2A (0.62) | KMT2AMAPK1ALDH1A1L3MBTL1GAA | |
| SCHEMBL784569 | 0.76 | MAPK1 (0.52) | KMT2AMAPK1ALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10781176-B2 | Catalytic hydrogenation of substituted cyanopyridines and process for preparing substituted pyridylmethylbenzamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-09-22 | — | — | US | disclosed |
| US-10647674-B2 | — | — | 2020-05-12 | — | — | US | disclosed |
| US-20180297952-A1 | CATALYTIC HYDROGENATION OF SUBSTITUTED CYANOPYRIDINES AND PROCESS FOR PREPARING SUBSTITUTED PYRIDYLMETHYLBENZAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647674-B2 | — | PYCR1, HCN4, PHYKPL | KMT2A 1082/4885MAPK1 1585/4885ALDH1A1 3685/4885 |
| US-20180297952-A1 | CATALYTIC HYDROGENATION OF SUBSTITUTED CYANOPYRIDINES AND PROCESS FOR PREPARING SUBSTITUTED PYRIDYLMETHYLBENZAMIDES | HCN4, PHYKPL, PYCR1 | KMT2A 535/4885MAPK1 1769/4885ALDH1A1 3619/4885 |
| US-10781176-B2 | Catalytic hydrogenation of substituted cyanopyridines and process for preparing substituted pyridylmethylbenzamides | HCN4, PHYKPL, PYCR1 | KMT2A 535/4885MAPK1 1769/4885ALDH1A1 3619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.