Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 4/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.40 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.40 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20534970 | 0.89 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10IKBKB | |
| SCHEMBL20535692 | 0.88 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10DHODH | |
| SCHEMBL20535965 | 0.85 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10IKBKB | |
| SCHEMBL20535680 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL20535044 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10IKBKB | |
| SCHEMBL20535014 | 0.82 | KDM4E (0.78) | KDM4EALDH1A1HPGDHSD17B10IKBKB | |
| SCHEMBL20535672 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL13699689 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10IKBKB | |
| SCHEMBL20535529 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL20534973 | 0.79 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018189683-A1 | BENZOFURAN DERIVATIVES FOR USE AS AMPK ACTIVATORS | UNIVERSITA' DI PISA (IT) | 2018-10-18 | — | — | WO | claimed |
| WO-2018189683-A1 | BENZOFURAN DERIVATIVES FOR USE AS AMPK ACTIVATORS | UNIVERSITA' DI PISA (IT) | 2018-10-18 | — | — | WO | disclosed |