Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | ICMT | O60725 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20534820 | 0.88 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10KIF11 | |
| SCHEMBL20534824 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10SLC9A1 | |
| SCHEMBL20535044 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL20535675 | 0.82 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL20534966 | 0.81 | KDM4E (0.72) | KDM4EALDH1A1HPGDHSD17B10SLC9A1 | |
| SCHEMBL20535057 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL20535529 | 0.79 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDHSD17B10SLC9A1 | |
| SCHEMBL20535965 | 0.79 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10PGR | |
| SCHEMBL20534970 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10KIF11 | |
| SCHEMBL20535680 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018189683-A1 | BENZOFURAN DERIVATIVES FOR USE AS AMPK ACTIVATORS | UNIVERSITA' DI PISA (IT) | 2018-10-18 | — | — | WO | claimed |
| WO-2018189683-A1 | BENZOFURAN DERIVATIVES FOR USE AS AMPK ACTIVATORS | UNIVERSITA' DI PISA (IT) | 2018-10-18 | — | — | WO | disclosed |