Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.45 |
| ▸ | XDH | P47989 | 2/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535952 | 0.90 | ALDH1A1 (0.52) | PGRXDHSLC22A12CSF1RKDM4E | |
| SCHEMBL20535051 | 0.88 | KDM4E (0.46) | PGRCSF1RKDM4EALDH1A1HPGD | |
| SCHEMBL13699672 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10IKBKB | |
| SCHEMBL13335731 | 0.82 | PLG (0.41) | PGRXDHSLC22A12CSF1RMAP4K4 | |
| SCHEMBL13335691 | 0.81 | XDH (0.42) | PGRXDHSLC22A12CSF1RMAP4K4 | |
| SCHEMBL20535696 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10IKBKB | |
| SCHEMBL3317797 | 0.81 | XDH (0.41) | PGRXDHSLC22A12CSF1RKDM4E | |
| SCHEMBL13335708 | 0.81 | MAPT (0.43) | PGRXDHSLC22A12CSF1RKDM4E | |
| SCHEMBL20534832 | 0.79 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDHSD17B10CDC7 | |
| SCHEMBL13335722 | 0.79 | XDH (0.40) | PGRXDHSLC22A12CSF1RMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018189683-A1 | BENZOFURAN DERIVATIVES FOR USE AS AMPK ACTIVATORS | UNIVERSITA' DI PISA (IT) | 2018-10-18 | — | — | WO | claimed |
| WO-2018189683-A1 | BENZOFURAN DERIVATIVES FOR USE AS AMPK ACTIVATORS | UNIVERSITA' DI PISA (IT) | 2018-10-18 | — | — | WO | disclosed |