Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535012 | 0.90 | PGR (0.45) | ALDH1A1KDM4EHPGDHSD17B10PGR | |
| SCHEMBL20534817 | 0.88 | KDM4E (0.56) | ALDH1A1KDM4EHPGDHSD17B10PGR | |
| SCHEMBL20535044 | 0.83 | KDM4E (0.61) | ALDH1A1KDM4EHPGDHSD17B10IKBKB | |
| SCHEMBL20535675 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10MAP4K4 | |
| SCHEMBL20534966 | 0.81 | KDM4E (0.72) | ALDH1A1KDM4EHPGDHSD17B10MAP4K4 | |
| SCHEMBL20535057 | 0.81 | KDM4E (0.56) | ALDH1A1KDM4EHPGDHSD17B10CDC7 | |
| SCHEMBL20534824 | 0.81 | KDM4E (0.59) | ALDH1A1KDM4EHPGDHSD17B10MAP4K4 | |
| SCHEMBL20535671 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10CDC7 | |
| SCHEMBL20535051 | 0.78 | KDM4E (0.46) | ALDH1A1KDM4EHPGDHSD17B10PGR | |
| SCHEMBL20535680 | 0.77 | KDM4E (0.61) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018189683-A1 | BENZOFURAN DERIVATIVES FOR USE AS AMPK ACTIVATORS | UNIVERSITA' DI PISA (IT) | 2018-10-18 | — | — | WO | claimed |
| WO-2018189683-A1 | BENZOFURAN DERIVATIVES FOR USE AS AMPK ACTIVATORS | UNIVERSITA' DI PISA (IT) | 2018-10-18 | — | — | WO | disclosed |