Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 4/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535226 | 0.87 | KDM4E (0.40) | HRH3DPP4DPP7KDM4ECCR5 | |
| SCHEMBL20535908 | 0.81 | LMNA (0.41) | HRH3DPP7KDM4ECYP2D6CYP1A2 | |
| SCHEMBL21216253 | 0.81 | KDM1A (0.42) | FKBP1AKDM4EATMLMNA | |
| SCHEMBL21202236 | 0.81 | KDM1A (0.42) | FKBP1AKDM4EATMLMNA | |
| SCHEMBL21216118 | 0.65 | KDM1A (0.46) | HRH3KDM4EATM | |
| SCHEMBL28472037 | 0.65 | KDM4E (0.49) | HRH3DPP7KDM4E | |
| SCHEMBL6819563 | 0.62 | AOC3 (0.53) | KDM4EL3MBTL1TSHRLMNA | |
| SCHEMBL4407771 | 0.62 | AOC3 (0.53) | KDM4EL3MBTL1TSHRLMNA | |
| SCHEMBL5177116 | 0.62 | KDM1A (0.46) | FKBP1AATMCYP2D6CYP1A2LMNA | |
| SCHEMBL21216112 | 0.62 | JAK2 (0.44) | HRH3KDM4EATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609866-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | Evonetix Ltd (GB) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018189546-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | EVONETIX LTD (GB) | 2018-10-18 | — | — | WO | disclosed |