Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535908 | 0.91 | LMNA (0.41) | KDM4ELMNAHRH3DPP7MEN1 | |
| SCHEMBL20535227 | 0.87 | FKBP1A (0.36) | KDM4ELMNAHRH3DPP4DPP7 | |
| SCHEMBL21202236 | 0.79 | KDM1A (0.42) | KDM4ELMNA | |
| SCHEMBL21216253 | 0.79 | KDM1A (0.42) | KDM4ELMNA | |
| SCHEMBL28472037 | 0.74 | KDM4E (0.49) | KDM4EHRH3DPP7MEN1ALDH1A1 | |
| SCHEMBL20535219 | 0.71 | KDM4E (0.50) | KDM4ELMNAHRH3DPP7HTT | |
| SCHEMBL6540255 | 0.69 | DPP4 (0.57) | HRH3DPP4HTTALDH1A1 | |
| SCHEMBL1849603 | 0.68 | LMNA (0.77) | KDM4ELMNAMEN1KMT2APLA2G1B | |
| SCHEMBL2289990 | 0.68 | LMNA (0.77) | KDM4ELMNAMEN1KMT2APLA2G1B | |
| SCHEMBL7278068 | 0.68 | LMNA (0.77) | KDM4ELMNAMEN1KMT2APLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609866-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | Evonetix Ltd (GB) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018189546-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | EVONETIX LTD (GB) | 2018-10-18 | — | — | WO | disclosed |