Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21202236 | 1.00 | KDM1A (0.42) | KDM1AATMJAK2JAK1PRMT5 | |
| SCHEMBL20535908 | 0.86 | LMNA (0.41) | LMNAKDM4E | |
| SCHEMBL21216118 | 0.84 | KDM1A (0.46) | KDM1AATMJAK2JAK1PRMT5 | |
| SCHEMBL21216231 | 0.81 | JAK2 (0.44) | KDM1AATMJAK2JAK1PRMT5 | |
| SCHEMBL21216112 | 0.81 | JAK2 (0.44) | KDM1AATMJAK2JAK1PRMT5 | |
| SCHEMBL20535227 | 0.81 | FKBP1A (0.36) | ATMFKBP1ALMNAKDM4E | |
| SCHEMBL5177116 | 0.80 | KDM1A (0.46) | KDM1AATMPRMT5FKBP1ALMNA | |
| SCHEMBL5156033 | 0.79 | KDM1A (0.42) | KDM1AATMJAK2JAK1PRMT5 | |
| SCHEMBL5159359 | 0.79 | KDM1A (0.42) | KDM1AATMJAK2JAK1PRMT5 | |
| SCHEMBL20535226 | 0.79 | KDM4E (0.40) | LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019145713-A9 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | EVONETIX LTD (GB) | 2020-08-06 | — | — | WO | disclosed |
| WO-2019145713-A1 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | EVONETIX LTD (GB) | 2019-08-01 | — | — | WO | disclosed |