Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535274 | 0.89 | KDM4E (0.56) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL20534980 | 0.88 | KDM4E (0.47) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL20535271 | 0.85 | ALDH1A1 (0.45) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL20535045 | 0.85 | KDM4E (0.51) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL20535444 | 0.85 | KDM4E (0.47) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL13699672 | 0.83 | KDM4E (0.50) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL20535275 | 0.82 | SCN9A (0.43) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL20535056 | 0.82 | ICMT (0.47) | KDM4EHPGDALDH1A1MAPTNPC1 | |
| SCHEMBL20534989 | 0.82 | KDM4E (0.49) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL20535441 | 0.80 | KDM4E (0.50) | KDM4EHPGDALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018189683-A1 | BENZOFURAN DERIVATIVES FOR USE AS AMPK ACTIVATORS | UNIVERSITA' DI PISA (IT) | 2018-10-18 | — | — | WO | claimed |
| WO-2018189683-A1 | BENZOFURAN DERIVATIVES FOR USE AS AMPK ACTIVATORS | UNIVERSITA' DI PISA (IT) | 2018-10-18 | — | — | WO | disclosed |