Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535826 | 0.90 | MAPK1 (0.33) | — | |
| SCHEMBL16799731 | 0.78 | JAK2 (0.34) | — | |
| SCHEMBL20536176 | 0.68 | PRMT5 (0.33) | — | |
| SCHEMBL24469933 | 0.66 | PIK3CA (0.39) | MCHR1 | |
| SCHEMBL20262415 | 0.64 | XDH (0.37) | MCHR1GRM4XDH | |
| SCHEMBL20282527 | 0.64 | CNR1 (0.35) | GRM4XDH | |
| SCHEMBL1559517 | 0.63 | DAO (0.33) | — | |
| SCHEMBL20599456 | 0.61 | ALDH1A1 (0.31) | — | |
| SCHEMBL5269898 | 0.61 | GBA1 (0.50) | — | |
| SCHEMBL27689141 | 0.61 | GBA1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018191587-A1 | TAM KINASE INHIBITORS | SYROS PHARMACEUTICALS, INC. (US) | 2018-10-18 | — | — | WO | claimed |
| WO-2018191587-A1 | TAM KINASE INHIBITORS | SYROS PHARMACEUTICALS, INC. (US) | 2018-10-18 | — | — | WO | disclosed |