Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 4/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27516965 | 0.87 | CXCR2 (0.50) | CXCR2CXCR1ADRB3TSPOSLC6A3 | |
| SCHEMBL6825645 | 0.86 | CXCR2 (0.39) | CXCR2CXCR1ADRB3TSPOSLC6A3 | |
| SCHEMBL27566180 | 0.85 | CXCR2 (0.37) | CXCR2CXCR1ADRB3TSPOSLC6A3 | |
| SCHEMBL6823307 | 0.80 | CXCR1 (0.34) | CXCR2CXCR1KDM4EALDH1A1GAA | |
| SCHEMBL7506969 | 0.76 | CXCR2 (0.48) | CXCR2CXCR1ALDH1A1 | |
| SCHEMBL7171381 | 0.75 | CXCR2 (0.37) | CXCR2CXCR1ADRB3TSPOSLC6A3 | |
| SCHEMBL5594733 | 0.75 | MMP2 (0.39) | CXCR2CXCR1 | |
| SCHEMBL27499546 | 0.74 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL27587734 | 0.74 | CXCR2 (0.45) | CXCR2CXCR1 | |
| SCHEMBL27517286 | 0.74 | CXCR2 (0.45) | CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512465-A1 | USE OF COMPOUNDS IN THE TREATMENT OR PREVENTION OF SKIN DISORDERS | Galderma Research & Development (FR) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011073248-A1 | USE OF COMPOUNDS IN THE TREATMENT OR PREVENTION OF SKIN DISORDERS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-06-23 | — | — | WO | disclosed |
| CN-1539816-A | IL-8 receptor antagonists | ʷ��˿�������ȳ�ķ����˾ | 2004-10-27 | — | — | CN | disclosed |
| CN-1215990-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-05-05 | — | — | CN | disclosed |