Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 5/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | IDO1 | P14902 | 3/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1950469 | 0.84 | DRD4 (0.50) | MAPTTP53THRBIDO1KCNH2 | |
| SCHEMBL20537300 | 0.84 | SMN1; SMN2 (0.53) | MAPTSMN1; SMN2TP53THRBIDO1 | |
| SCHEMBL1948375 | 0.78 | DRD2 (0.51) | MAPTTHRBLMNAPOLB | |
| SCHEMBL1950866 | 0.78 | DRD2 (0.48) | MAPTTP53THRBIDO1KCNH2 | |
| SCHEMBL20536802 | 0.77 | KDM4E (0.53) | MAPTSMN1; SMN2 | |
| SCHEMBL25779984 | 0.76 | IDO1 (0.81) | MAPTTP53THRBIDO1KCNH2 | |
| SCHEMBL25780604 | 0.75 | TP53 (0.66) | MAPTSMN1; SMN2TP53THRBIDO1 | |
| SCHEMBL7409209 | 0.74 | IDO1 (0.60) | MAPTSMN1; SMN2TP53THRBIDO1 | |
| SCHEMBL1788003 | 0.74 | SMN1; SMN2 (0.53) | MAPTSMN1; SMN2TP53THRBIDO1 | |
| SCHEMBL22397728 | 0.74 | IDO1 (1.00) | MAPTTP53THRBIDO1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438055-B1 | DIHYDROINDOLE AND TETRAHYDROISOQUINOLINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL INHIBITORS | JAPAN TOBACCO INC (JP) | 2018-10-24 | — | — | EP | claimed |