SCHEMBL20537007

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3822715	0.87	HPGD (0.51)	HPGDTSHRMAPK1HSD17B10LIG1
	SCHEMBL978930	0.82	HPGD (0.50)	HPGDTSHRMAPK1HSD17B10LIG1
	1-Hydroxy-2-Allyloxybenzene SCHEMBL1562951	0.81	GAA (0.59)	HPGDTSHRMAPK1HSD17B10LIG1
	SCHEMBL20554231	0.79	TSHR (0.45)	HPGDTSHRMAPK1HSD17B10LIG1
	SCHEMBL7072808	0.79	HPGD (0.47)	HPGDTSHRMAPK1HSD17B10LIG1
	SCHEMBL15814879	0.77	CYP3A4 (0.49)	HPGDTSHRMAPK1HSD17B10LIG1
	SCHEMBL4865834	0.77	HPGD (0.46)	HPGDTSHRMAPK1HSD17B10LIG1
	SCHEMBL11883080	0.77	MEN1 (0.48)	HPGDMAPK1HSD17B10CYP3A4MAPT
	SCHEMBL15946499	0.77	ALDH1A1 (0.41)	HPGDTSHRMAPK1HSD17B10CYP3A4
	SCHEMBL4192226	0.76	HPGD (0.45)	HPGDTSHRMAPK1HSD17B10LIG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.