SCHEMBL20543181

SCHEMBL20543181

Cc1cccc(C(=O)OCc2cc(=O)c(O)co2)c1O

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DAO P14920 3/20 0.51
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
ELANE P08246 3/20 0.49
TYR P14679 3/20 0.49
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL359337 0.89 DAO (0.52) DAOELANETYRPOLBGAA
SCHEMBL20543223 0.86 PPARG (0.59) DAOELANETYRPOLBGAA
SCHEMBL361245 0.83 DAO (0.58) DAOELANETYR
SCHEMBL20543148 0.81 DAO (0.55) DAOELANETYRPOLBGAA
SCHEMBL20543161 0.80 DAO (0.54) DAOELANETYRPOLBGAA
SCHEMBL7550581 0.79 POLB (0.60) DAOELANETYRPOLBGAA
SCHEMBL9085769 0.78 SERPINE1 (0.56) DAOELANETYR
SCHEMBL7558334 0.77 POLB (0.63) DAOELANETYRPOLBGAA
SCHEMBL360885 0.77 POLB (0.57) DAOELANETYRPOLBGAA
SCHEMBL3220810 0.77 DAO (0.63) DAOELANETYRPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180370940-A1 SALICYLIC ACID DERIVATIVE, METHOD FOR PREPARING SAME, AND COSMETIC COMPOSITION FOR WHITENING COMPRISING SAME AMOREPACIFIC CORPORATION (KR) 2018-12-27 US claimed
EP-3395807-A1 SALICYLIC ACID DERIVATIVE, METHOD FOR PREPARING SAME, AND COSMETIC COMPOSITION FOR WHITENING COMPRISING SAME Amorepacific Corporation (KR) 2018-10-31 EP claimed
EP-3395807-B1 SALICYLIC ACID DERIVATIVE, METHOD FOR PREPARING SAME, AND COSMETIC COMPOSITION FOR WHITENING COMPRISING SAME AMOREPACIFIC CORP (KR) 2020-10-14 EP disclosed
EP-3395807-B1 SALICYLIC ACID DERIVATIVE, METHOD FOR PREPARING SAME, AND COSMETIC COMPOSITION FOR WHITENING COMPRISING SAME AMOREPACIFIC CORP (KR) 2020-10-14 EP disclosed
US-20180370940-A1 SALICYLIC ACID DERIVATIVE, METHOD FOR PREPARING SAME, AND COSMETIC COMPOSITION FOR WHITENING COMPRISING SAME AMOREPACIFIC CORPORATION (KR) 2018-12-27 US disclosed
EP-3395807-A1 SALICYLIC ACID DERIVATIVE, METHOD FOR PREPARING SAME, AND COSMETIC COMPOSITION FOR WHITENING COMPRISING SAME Amorepacific Corporation (KR) 2018-10-31 EP disclosed
CN-108473458-A Bigcatkin willow acid derivative compound, preparation method and the skin-lightening cosmetic constituent comprising the compound 爱茉莉太平洋股份有限公司 2018-08-31 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180370940-A1 SALICYLIC ACID DERIVATIVE, METHOD FOR PREPARING SAME, AND COSMETIC COMPOSITION FOR WHITENING COMPRISING SAME TYR, DDC, KMO DAO 10/4885NPC1 4498/4885RAB9A 4276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.