Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.73 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | F7 | P08709 | 3/20 | 0.55 |
| ▸ | F3 | P13726 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | PPARD | Q03181 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | FABP3 | P05413 | 2/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | FABP4 | P15090 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073304 | 1.00 | TSHR (0.73) | TSHRTRPV1ALDH1A1KDM4EF7 | |
| SCHEMBL30605577 | 1.00 | TSHR (0.73) | TSHRTRPV1ALDH1A1KDM4EF7 | |
| SCHEMBL29869078 | 1.00 | TSHR (0.73) | TSHRTRPV1ALDH1A1KDM4EF7 | |
| SCHEMBL11073391 | 1.00 | TSHR (0.73) | TSHRTRPV1ALDH1A1KDM4EF7 | |
| SCHEMBL11073390 | 1.00 | TSHR (0.73) | TSHRTRPV1ALDH1A1KDM4EF7 | |
| SCHEMBL1296303 | 1.00 | TSHR (0.73) | TSHRTRPV1ALDH1A1KDM4EF7 | |
| SCHEMBL9155807 | 1.00 | TSHR (0.73) | TSHRTRPV1ALDH1A1KDM4EF7 | |
| SCHEMBL1296302 | 1.00 | TSHR (0.73) | TSHRTRPV1ALDH1A1KDM4EF7 | |
| SCHEMBL9155814 | 1.00 | TSHR (0.73) | TSHRTRPV1ALDH1A1KDM4EF7 | |
| SCHEMBL25185268 | 0.98 | TSHR (0.70) | TSHRTRPV1ALDH1A1KDM4EF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11471533-B2 | Compound usable as cationic lipid | KYOWA KIRIN CO., LTD. (JP) | 2022-10-18 | — | — | US | disclosed |
| EP-3521270-B1 | CATIONIC LIPID COMPOUND | KYOWA KIRIN CO LTD (JP) | 2022-06-29 | — | — | EP | disclosed |
| US-20210275672-A1 | COMPOUND USABLE AS CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2021-09-09 | — | — | US | disclosed |
| US-20200368173-A1 | NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE | KYOWA KIRIN CO., LTD. (JP) | 2020-11-26 | — | — | US | disclosed |
| EP-3662913-A1 | NUCLEIC-ACID-CONTAINING LIPID NANOPARTICLES | Kyowa Kirin Co., Ltd. (JP) | 2020-06-10 | — | — | EP | disclosed |
| EP-3521270-A1 | CATIONIC LIPID COMPOUND | Kyowa Hakko Kirin Co., Ltd. (JP) | 2019-08-07 | — | — | EP | disclosed |
| US-20190008975-A1 | COMPOUND AS CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2019-01-10 | — | — | US | disclosed |
| EP-3395797-A1 | COMPOUNDS AS CATIONIC LIPIDS | Kyowa Hakko Kirin Co., Ltd. (JP) | 2018-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11471533-B2 | Compound usable as cationic lipid | NPC1L1, PLIN1, PLIN5 | TSHR 3958/4885TRPV1 834/4885ALDH1A1 3708/4885 |
| US-20210275672-A1 | COMPOUND USABLE AS CATIONIC LIPID | NPC1L1, PLIN1, PLIN5 | TSHR 3958/4885TRPV1 834/4885ALDH1A1 3708/4885 |
| US-20190008975-A1 | COMPOUND AS CATIONIC LIPID | NPC1L1, LIPA, CETP | TSHR 2967/4885TRPV1 314/4885ALDH1A1 2340/4885 |
| US-20200368173-A1 | NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE | LIPA, LIPC, PNLIP | TSHR 3238/4885TRPV1 3502/4885ALDH1A1 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.