Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901402 | 0.76 | NPC1 (0.46) | NPC1RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL9901401 | 0.76 | NPC1 (0.46) | NPC1RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL27503360 | 0.76 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL1095279 | 0.70 | — | — | |
| SCHEMBL1095276 | 0.70 | — | — | |
| SCHEMBL5433410 | 0.67 | — | — | |
| SCHEMBL528074 | 0.67 | — | — | |
| SCHEMBL4320351 | 0.67 | NPC1 (0.46) | NPC1RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL506938 | 0.67 | RAB9A (0.46) | NPC1RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL2358163 | 0.67 | NPC1 (0.54) | NPC1RAB9AALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108601351-B | 2-amino-5-ketoxime-pyrimidine derivatives and their use for controlling undesired vegetation | 拜耳作物科学股份公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-108601351-B | 2-amino-5-ketoxime-pyrimidine derivatives and their use for controlling undesired vegetation | 拜耳作物科学股份公司 | 2020-12-11 | — | — | CN | disclosed |
| US-10806142-B2 | 2-amino-5-ketoxime-pyrimidine derivatives and their use for controlling undesired plant growth | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-10-20 | — | — | US | disclosed |
| US-10806142-B2 | 2-amino-5-ketoxime-pyrimidine derivatives and their use for controlling undesired plant growth | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-10-20 | — | — | US | disclosed |
| EP-3606915-A1 | 2-AMINO-5-OXYALKYL-PYRIMIDINE DERIVATIVES AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH | Bayer CropScience Aktiengesellschaft (DE) | 2020-02-12 | — | — | EP | disclosed |
| US-20200029565-A1 | 2-AMINO-5-OXYALKYL-PYRIMIDINE DERIVATIVES AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH | BAYER AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| EP-3393244-B1 | 2-AMINO-5-KETOXIM PYRIMIDINE DERIVATIVES AND USE THEREOF FOR COMBATING UNDESIRED PLANT GROWTH | BAYER CROPSCIENCE AG (DE) | 2019-12-18 | — | — | EP | disclosed |
| CN-110461833-A | 2- amino -5- oxygroup alkyl derivative and its purposes for preventing and treating undesirable plant growth | BAYER CROPSCIENCE AG | 2019-11-15 | — | — | CN | disclosed |
| US-20190082692-A1 | 2-AMINO-5-KETOXIME-PYRIMIDINE DERIVATIVES AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-03-21 | — | — | US | disclosed |
| EP-3393244-A1 | 2-AMINO-5-KETOXIME-PYRIMIDINE DERIVATIVES AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH | Bayer CropScience Aktiengesellschaft (DE) | 2018-10-31 | — | — | EP | disclosed |
| CN-108601351-A | 2-amino-5-ketoxime-pyrimidine derivatives and their use for controlling undesired vegetation | 拜耳作物科学股份公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108601351-A | 2-amino-5-ketoxime-pyrimidine derivatives and their use for controlling undesired vegetation | 拜耳作物科学股份公司 | 2018-09-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200029565-A1 | 2-AMINO-5-OXYALKYL-PYRIMIDINE DERIVATIVES AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH | PFAS, ODC1, GART | NPC1 4345/4885RAB9A 1927/4885ALDH1A1 1679/4885 |
| US-20190082692-A1 | 2-AMINO-5-KETOXIME-PYRIMIDINE DERIVATIVES AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH | TKT, TYMS, TK2 | NPC1 4757/4885RAB9A 2907/4885ALDH1A1 1325/4885 |
| US-10806142-B2 | 2-amino-5-ketoxime-pyrimidine derivatives and their use for controlling undesired plant growth | TKT, TYMS, TK2 | NPC1 4757/4885RAB9A 2907/4885ALDH1A1 1325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.