Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683926 | 0.84 | ALOX5 (0.50) | CYP2D6LMNAMAPK1SLC6A3ALDH1A1 | |
| SCHEMBL8674588 | 0.84 | SLC6A3 (0.42) | CYP2D6SRCLMNAMAPK1SLC6A3 | |
| SCHEMBL16102369 | 0.80 | CYP2D6 (0.43) | CYP2D6SRCLMNAMAPK1PTGS2 | |
| SCHEMBL10996556 | 0.77 | LMNA (0.52) | CYP2D6SRCLMNAMAPK1SLC6A3 | |
| SCHEMBL10955738 | 0.76 | ALDH1A1 (0.50) | CYP2D6LMNASLC6A3ALDH1A1KDM4E | |
| SCHEMBL24059868 | 0.74 | CYP2D6 (0.38) | CYP2D6SRCLMNAMAPK1PTGS2 | |
| SCHEMBL22198538 | 0.74 | HPGD (0.42) | CYP2D6SRCLMNAMAPK1PTGS2 | |
| SCHEMBL20544320 | 0.74 | KDM4E (0.40) | CYP2D6SRCLMNAMAPK1PTGS2 | |
| SCHEMBL776890 | 0.74 | TSHR (0.48) | CYP2D6SRCSLC6A3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2007795 | 0.73 | PTGS2 (0.72) | CYP2D6SRCLMNAMAPK1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719168-A | Acetamide derivatives and their use as feeding behaviour modifiers | LABORATOIRE L. LAFON (FR) | 1998-02-17 | — | — | US | disclosed |
| US-4964893-A | REDUCING INJURY TO A CROP PLANT | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |