Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | RARB | P10826 | 8/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5370893 | 0.82 | CYP3A4 (0.53) | PPARGMEN1KMT2AMAPTNR1I2 | |
| SCHEMBL5482646 | 0.82 | PPARG (0.45) | PPARGLTB4R2MAPTBCAT2ALDH1A1 | |
| SCHEMBL27405674 | 0.81 | LMNA (0.55) | PPARGMEN1KMT2AMAPTNR1I2 | |
| SCHEMBL6535320 | 0.81 | LMNA (0.55) | PPARGMEN1KMT2AMAPTNR1I2 | |
| SCHEMBL28371050 | 0.81 | LMNA (0.55) | PPARGMEN1KMT2AMAPTNR1I2 | |
| SCHEMBL9051704 | 0.80 | MAPT (0.46) | PPARGMEN1KMT2AMAPTNR1I2 | |
| SCHEMBL1004987 | 0.79 | PPARA (0.53) | MKNK1MKNK2PPARGRARBMEN1 | |
| SCHEMBL5476512 | 0.79 | BCAT2 (0.59) | PPARGLTB4R2MEN1KMT2AMAPT | |
| SCHEMBL9050807 | 0.78 | MEN1 (0.42) | PPARGLTB4R2MEN1KMT2AMAPT | |
| SCHEMBL6013405 | 0.78 | CXCR5 (0.51) | PPARGRARBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10550073-B2 | Benzamide derivative | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) | 2020-02-04 | — | — | US | disclosed |
| US-20180312462-A1 | BENZAMIDE DERIVATIVE | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) | 2018-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312462-A1 | BENZAMIDE DERIVATIVE | CYP3A5, ABCB1, CYP2D6 | MKNK1 4865/4885MKNK2 4818/4885PPARG 917/4885 |
| US-10550073-B2 | Benzamide derivative | CYP3A5, ABCB1, CYP2D6 | MKNK1 4865/4885MKNK2 4818/4885PPARG 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.