Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17987402 | 0.86 | CYP11B2 (0.58) | CYP11B2MEN1ALDH1A1KMT2ALOXL2 | |
| SCHEMBL17963580 | 0.81 | ALDH1A1 (0.41) | MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL17987316 | 0.80 | RAB9A (0.45) | CYP11B2MEN1ALDH1A1KMT2ALOXL2 | |
| SCHEMBL17987307 | 0.80 | ALDH1A1 (0.41) | MEN1ALDH1A1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL17987359 | 0.79 | MEN1 (0.41) | MEN1ALDH1A1KMT2A | |
| SCHEMBL17963592 | 0.78 | MEN1 (0.41) | MEN1ALDH1A1KMT2A | |
| SCHEMBL17987295 | 0.78 | ALDH1A1 (0.49) | CYP11B2MEN1ALDH1A1KMT2ALOXL2 | |
| SCHEMBL17963588 | 0.76 | MEN1 (0.40) | CYP11B2MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL17987357 | 0.75 | ALDH1A1 (0.43) | CYP11B2MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL17987308 | 0.74 | CYP11B2 (0.44) | CYP11B2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3250569-B1 | ALDOSTERONE SYNTHASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2019-01-09 | — | — | EP | disclosed |
| US-10131642-B1 | Aldosterone synthase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-11-20 | — | — | US | disclosed |
| US-20180312475-A1 | ALDOSTERONE SYNTHASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312475-A1 | ALDOSTERONE SYNTHASE INHIBITORS | CYP21A2, CYP11B1, CYP17A1 | CYP11B2 5/4885MEN1 610/4885ALDH1A1 250/4885 |
| US-10131642-B1 | Aldosterone synthase inhibitors | CYP21A2, CYP11B1, CYP17A1 | CYP11B2 5/4885MEN1 610/4885ALDH1A1 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.