Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78389 | 1.00 | L3MBTL1 (0.59) | L3MBTL1TSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL18011765 | 1.00 | L3MBTL1 (0.59) | L3MBTL1TSHRALOX15HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8118571 | 0.98 | L3MBTL1 (0.57) | L3MBTL1TSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL31677054 | 0.98 | L3MBTL1 (0.57) | L3MBTL1TSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL13893262 | 0.98 | L3MBTL1 (0.57) | L3MBTL1TSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL11742016 | 0.92 | L3MBTL1 (0.52) | L3MBTL1TSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL773501 | 0.92 | L3MBTL1 (0.52) | L3MBTL1TSHRALOX15HSD17B10ALDH1A1 | |
| Propionic Acid SCHEMBL23466968 | 0.88 | ALDH1A1 (0.49) | L3MBTL1TSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL22196916 | 0.87 | ALOX15 (0.72) | L3MBTL1TSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL18633170 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024177503-A1 | STABILIZED NATIVE PROTEIN COMPLEXES CONJUGATED WITH BRANCHED MOLECULES | STICHTING VU (NL) | 2024-08-29 | — | — | WO | disclosed |
| US-11241473-B2 | Bicyclic peptide ligands and uses thereof | BICYCLETX LIMITED (GB) | 2022-02-08 | — | — | US | disclosed |
| US-11241473-B2 | Bicyclic peptide ligands and uses thereof | BICYCLETX LIMITED (GB) | 2022-02-08 | — | — | US | disclosed |
| US-20210046145-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | BICYCLETX LIMITED (GB) | 2021-02-18 | — | — | US | disclosed |
| US-20210046145-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | BICYCLETX LIMITED (GB) | 2021-02-18 | — | — | US | disclosed |
| US-10857196-B2 | Bicyclic peptide ligands and uses thereof | BICYCLETX LIMITED (GB) | 2020-12-08 | — | — | US | disclosed |
| US-10857196-B2 | Bicyclic peptide ligands and uses thereof | BICYCLETX LIMITED (GB) | 2020-12-08 | — | — | US | disclosed |
| US-20180311300-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | BICYCLETX LIMITED (GB) | 2018-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10857196-B2 | Bicyclic peptide ligands and uses thereof | VIP, NGLY1, BID | L3MBTL1 1883/4885TSHR 1216/4885ALOX15 3936/4885 |
| US-20180311300-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | VIP, NGLY1, BID | L3MBTL1 1883/4885TSHR 1216/4885ALOX15 3936/4885 |
| US-20210046145-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | VIP, NGLY1, BID | L3MBTL1 1883/4885TSHR 1216/4885ALOX15 3936/4885 |
| US-11241473-B2 | Bicyclic peptide ligands and uses thereof | VIP, NGLY1, BID | L3MBTL1 1883/4885TSHR 1216/4885ALOX15 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.