Sugi Predict

Sugi Predict / Compounds / SCHEMBL78389

SCHEMBL78389

SCHEMBL78389

O=C(CCl)N1CCOCC1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.59
▸ TSHR P16473 2/20 0.54
▸ ALOX15 P16050 1/20 0.54
▸ HSD17B10 Q99714 1/20 0.54
▸ ALDH1A1 P00352 3/20 0.52
▸ SMN1; SMN2 Q16637 3/20 0.48
▸ POLB P06746 3/20 0.48
▸ GAA P10253 1/20 0.48
▸ HTT P42858 1/20 0.48
▸ CA12 O43570 1/20 0.48
▸ CA1 P00915 1/20 0.48
▸ CA9 Q16790 1/20 0.48
▸ KMT2A Q03164 2/20 0.47
▸ GLA P06280 1/20 0.47
▸ LMNA P02545 1/20 0.47
▸ TP53 P04637 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ FKBP1A P62942 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20547280 1.00 L3MBTL1 (0.59) L3MBTL1TSHRALOX15HSD17B10ALDH1A1
SCHEMBL18011765 1.00 L3MBTL1 (0.59) L3MBTL1TSHRALOX15HSD17B10ALDH1A1
Hydrochloric Acid SCHEMBL8118571 0.98 L3MBTL1 (0.57) L3MBTL1TSHRALOX15HSD17B10ALDH1A1
SCHEMBL31677054 0.98 L3MBTL1 (0.57) L3MBTL1TSHRALOX15HSD17B10ALDH1A1
SCHEMBL13893262 0.98 L3MBTL1 (0.57) L3MBTL1TSHRALOX15HSD17B10ALDH1A1
SCHEMBL11742016 0.92 L3MBTL1 (0.52) L3MBTL1TSHRALOX15HSD17B10ALDH1A1
SCHEMBL773501 0.92 L3MBTL1 (0.52) L3MBTL1TSHRALOX15HSD17B10ALDH1A1
Propionic Acid SCHEMBL23466968 0.88 ALDH1A1 (0.49) L3MBTL1TSHRALOX15HSD17B10ALDH1A1
SCHEMBL22196916 0.87 ALOX15 (0.72) L3MBTL1TSHRALOX15HSD17B10ALDH1A1
SCHEMBL18633170 0.86 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119874601-A 3, 3-Dimethyl-1, 2,3, 4-tetrahydro-9H-carbazole derivative and preparation method and application thereof 山东大学 2025-04-25 — — CN claimed
CN-115819342-B Carboxylesterase 2 fluorescent probe and synthetic method and application thereof 中国科学院大连化学物理研究所 2025-02-11 — — CN claimed
CN-113501819-B Pyridoimidazole substituted quinazolinone derivative, and synthetic method and application thereof 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2024-02-02 — — CN claimed
CN-113461661-B 6- (pyridin-3-yl) quinazoline-4 (3H) -ketone derivative and preparation and application thereof 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2023-11-28 — — CN claimed
CN-115819342-A Carboxylesterase 2 fluorescent probe and synthetic method and application thereof 中国科学院大连化学物理研究所 2023-03-21 — — CN claimed
CN-106008306-A Substituted indole derivatives, and preparation method and application thereof 山东大学 2016-10-12 — — CN claimed
EP-4288426-B1 QUINOXALINE DERIVATIVES AND USES THEREOF BLACK DIAMOND THERAPEUTICS INC (US) 2026-02-04 — — EP disclosed
US-20250368608-A1 SELECTIVE HDAC6 INHIBITOR ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) 2025-12-04 — — US disclosed
US-12472166-B2 Inhibition of mycobacterial type VII secretion STICHTING VUMC (NL) 2025-11-18 — — US disclosed
CN-120927841-A Gas phase detection method for monitoring synthesis of 4- (2-chloroacetyl) morpholine 扬州市普林斯医药科技有限公司 2025-11-11 — — CN disclosed
CN-120927841-A Gas phase detection method for monitoring synthesis of 4- (2-chloroacetyl) morpholine 扬州市普林斯医药科技有限公司 2025-11-11 — — CN disclosed
US-20250326754-A1 DNA-PK Inhibitor Compounds and Uses Thereof ADMARE THERAPEUTICS SOC (CA) 2025-10-23 — — US disclosed
EP-4626427-A1 COMBINATIONS COMPRISING A MENIN-MLL INHIBITOR AND A BCL-2 INHIBITOR Janssen Pharmaceutica NV (BE) 2025-10-08 — — EP disclosed
US-3942972-A Dioxolane substituted α-haloanilides as herbicides VELSICOL CHEMICAL CORPORATION (US) 1976-03-09 — — US disclosed
US-3941580-A N,N-BIS(2-METHOXY-3,6-DICHLORO-BENZOYL-OXYALKYL) ANILINES VELSICOL CHEMICAL CORPORATION (US) 1976-03-02 — — US disclosed
US-3940259-A Dioxane substituted-α-haloanilides as herbicides VELSICOL CHEMICAL CORPORATION (US) 1976-02-24 — — US disclosed
US-3933839-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-01-20 — — US disclosed
US-3932438-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-01-13 — — US disclosed
US-3932410-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-01-13 — — US disclosed
US-3931209-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368608-A1 SELECTIVE HDAC6 INHIBITOR HDAC6, HDAC3, HDAC1 L3MBTL1 3884/4885TSHR 651/4885ALOX15 3561/4885
US-12472166-B2 Inhibition of mycobacterial type VII secretion CFTR, ABCB11, ABCC2 L3MBTL1 1534/4885TSHR 609/4885ALOX15 4418/4885
US-20250326754-A1 DNA-PK Inhibitor Compounds and Uses Thereof DCK, CHEK1, CHEK2 L3MBTL1 1331/4885TSHR 4390/4885ALOX15 4857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.