SCHEMBL20547845

SCHEMBL20547845

NC(CCl)c1cnc(Cl)s1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SLC6A3 Q01959 1/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 2/20 0.30
ALDH1A1 P00352 2/20 0.30
GAA P10253 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20547842 1.00 CYP1A2 (0.33) CYP1A2CYP2C9CYP2C19SLC6A3KMT2A
Hydrochloric Acid SCHEMBL20521263 0.98 CYP1A2 (0.33) CYP1A2CYP2C9CYP2C19SLC6A3KMT2A
Hydrochloric Acid SCHEMBL20548189 0.98 CYP1A2 (0.33) CYP1A2CYP2C9CYP2C19SLC6A3KMT2A
Hydrochloric Acid SCHEMBL28689071 0.77 KMT2A (0.31) KMT2AMEN1ALDH1A1
SCHEMBL10184046 0.75
SCHEMBL9654892 0.72
SCHEMBL28447284 0.71 TAAR1 (0.35) CYP1A2CYP2C9CYP2C19SLC6A3KMT2A
SCHEMBL12671951 0.70
SCHEMBL20093614 0.69 L3MBTL1 (0.38) CYP1A2CYP2C9CYP2C19SLC6A3KMT2A
SCHEMBL7999561 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110546153-B Process for preparing optically active 2, 3-dihydrothiazolo [3,2-A ] pyrimidin-4-ium compounds 巴斯夫欧洲公司 2022-09-06 CN disclosed
US-20220046924-A1 METHOD FOR CONTROLLING PESTS OF POTATO PLANTS BASF SE (DE) 2022-02-17 US disclosed
US-20210368794-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND BASF SE (DE) 2021-12-02 US disclosed
EP-3615543-B1 PROCESS FOR PREPARING OPTICALLY ACTIVE 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2021-10-20 EP disclosed
US-11124528-B2 Process for preparing optically active 2,3-dihydrothiazolo[3,2-A]pyrimidin-4-ium compounds BASF SE (DE) 2021-09-21 US disclosed
WO-2020064501-A1 METHOD FOR CONTROLLING PESTS OF CITRUS PLANTS BASF SE (DE) 2020-04-02 WO disclosed
WO-2020064408-A1 METHOD OF CONTROLLING INSECTICIDE RESISTANT INSECTS AND VIRUS TRANSMISSION TO PLANTS BASF SE (DE) 2020-04-02 WO disclosed
WO-2020064503-A1 METHOD FOR CONTROLLING PESTS OF RAPESEED PLANTS BASF SE (DE) 2020-04-02 WO disclosed
EP-3628157-A1 METHOD OF CONTROLLING INSECTICIDE RESISTANT INSECTS AND VIRUS TRANSMISSION TO PLANTS BASF SE (DE) 2020-04-01 EP disclosed
EP-3628158-A1 PESTICIDAL MIXTURE COMPRISING A MESOIONIC COMPOUND AND A BIOPESTICIDE BASF SE (DE) 2020-04-01 EP disclosed
EP-3628156-A1 METHOD FOR CONTROLLING PESTS OF SUGARCANE, CITRUS, RAPESEED, AND POTATO PLANTS BASF SE (DE) 2020-04-01 EP disclosed
WO-2020058010-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND BASF SE (DE) 2020-03-26 WO disclosed
EP-3615543-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2020-03-04 EP disclosed
US-20200055872-A1 Process for Preparing Optically Active 2,3-Dihydrothiazolo[3,2-A]pyrimidin-4-ium Compounds BASF SE (DE) 2020-02-20 US disclosed
CN-110546153-A process for preparing optically active 2, 3-dihydrothiazolo [3,2-A ] pyrimidin-4-ium compounds BASF SE 2019-12-06 CN disclosed
WO-2018197541-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2018-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200055872-A1 Process for Preparing Optically Active 2,3-Dihydrothiazolo[3,2-A]pyrimidin-4-ium Compounds UMPS, UGP2, UGT1A4 CYP1A2 64/4885CYP2C9 105/4885CYP2C19 39/4885
US-11124528-B2 Process for preparing optically active 2,3-dihydrothiazolo[3,2-A]pyrimidin-4-ium compounds UMPS, UGP2, UGT1A4 CYP1A2 64/4885CYP2C9 105/4885CYP2C19 39/4885
US-20220046924-A1 METHOD FOR CONTROLLING PESTS OF POTATO PLANTS STOM, DDT, PIR CYP1A2 3379/4885CYP2C9 2723/4885CYP2C19 2702/4885
US-20210368794-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND ACHE, DDT, MTX2 CYP1A2 151/4885CYP2C9 674/4885CYP2C19 887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.